Home Chemistry Organic Building Blocks Bromides 2-Bromo-6-Fluorobenzoic Acid
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—COOH,—F).
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
Neutralization Reaction with Bases: Benzoic acid can react with bases to form water-soluble salts called benzoates. The reaction is a typical acid-base neutralization reaction, where the hydrogen ion from the carboxylic acid group is replaced by a metal cation or another positively charged organic group.
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
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2-Bromo-6-fluoro-3-methylbenzoic acid
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2-Bromo-4-chloro-6-fluorobenzoic acid
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6-Bromo-2-fluoro-3-(trifluoromethyl)benzoic acid
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6-Bromo-2-fluoro-3-(trifluoromethoxy)benzoic acid
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