Home Chemistry Heterocyclic Building Blocks Pyrrolidines Methyl Prolinate
Ester Hydrolysis: Under acidic or basic conditions, methyl prolinate can undergo hydrolysis to form proline and methanol.
Esterification: Methyl prolinate can react with carboxylic acids or acid derivatives to form esters through esterification reactions.
Amide Formation: It can react with amines to form amides through amidation reactions.
Reduction: The carbonyl group in methyl prolinate can be reduced to form the corresponding alcohol using reducing agents such as lithium aluminum hydride.
Substitution Reactions: The carbonyl group in methyl prolinate can undergo substitution reactions, such as nucleophilic substitution or electrophilic substitution.
Decarboxylation: Under certain conditions, such as heating or treatment with specific reagents, decarboxylation may occur, leading to the loss of the carboxyl group and formation of the corresponding alkylamine.
Condensation Reactions: Methyl prolinate can participate in condensation reactions with other carbonyl compounds to form cyclic compounds or larger molecules.
Ring-opening Reactions: The lactam ring in methyl prolinate may undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
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(2S,4S)-Methyl 4-fluoropyrrolidine-2-carboxylate hydrochloride
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(2S,4S)-1-tert-Butyl 2-methyl 4-chloropyrrolidine-1,2-dicarboxylate
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(2S,4R)-Methyl 4-(tert-butoxycarbonylamino)pyrrolidine-2-carboxylate
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(2R,4S)-Methyl 4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylate hydrochloride
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(R)-Methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride
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(2S,4R)-Methyl 4-fluoropyrrolidine-2-carboxylate hydrochloride
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Methyl (2S,4R)-4-Boc-aminopyrrolidine-2-carboxylate hydrochloride
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Boc-trans-4-fluoro-L-proline methyl ester
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(S)-1-tert-Butyl 2-methyl 4,4-difluoropyrrolidine-1,2-dicarboxylate
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(2R,4R)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate hydrochloride
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