Home Chemistry Heterocyclic Building Blocks Piperidines 4-Benzylpiperidine
Amination: You can introduce amine groups onto the piperidine ring through various reactions, such as reductive amination or nucleophilic substitution. These reactions can be used to functionalize the molecule further.
Alkylation: 4-benzylpiperidine can undergo alkylation reactions, where alkyl groups (-CH3, -C2H5, etc.) are introduced onto the piperidine ring. For instance, you can react it with alkyl halides to form N-alkylated products.
Reduction: The benzyl group in 4-benzylpiperidine can be reduced to a saturated alkyl group (e.g., by catalytic hydrogenation) to yield 4-methylpiperidine.
Oxidation: The molecule can be oxidized to introduce oxygen-containing functional groups. For example, the benzyl group can be oxidized to form a benzoic acid group (-COOH) using strong oxidizing agents.
Heterocycle formation: You can use 4-benzylpiperidine as a starting material to form other heterocycles through various reactions, such as cyclization reactions.
Substitution reactions: The benzyl group can undergo substitution reactions, where it can be replaced by other groups or functionalized in different ways, depending on the reaction conditions.
Halogenation: You can introduce halogen atoms (Cl, Br, I, etc.) onto the benzyl group or the piperidine ring through halogenation reactions.
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Methyl 4-(piperidin-4-ylmethyl)benzoate HCl
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4-(3-Chlorobenzyl)piperidine monohydrochloride
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tert-Butyl 4-(4-aminobenzyl)piperidine-1-carboxylate
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tert-Butyl 4-[hydroxy(phenyl)methyl]piperidine-1-carboxylate
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tert-Butyl 4-benzyl-3,3-difluoropiperidine-1-carboxylate
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4-(Piperidin-4-ylmethyl)benzamide hydrochloride
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4-(2-Fluorobenzyl)piperidine hydrochloride
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4-Benzyl-3,3-difluoropiperidine hydrochloride
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4-(4-Chlorobenzyl)piperidine hydrochloride
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4-(3,4-Dichlorobenzyl)piperidine hydrochloride
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