Home Chemistry Heterocyclic Building Blocks Furans N-(Furan-2-Ylmethyl)Aniline
Acylation: N-(furan-2-ylmethyl)aniline can undergo acylation reactions, where an acyl group (e.g., acetyl, benzoyl) is added to the nitrogen atom of the aniline group. This can be achieved usingacyl chloridesoranhydridesin the presence of a suitable base.
Amination: N-(furan-2-ylmethyl)aniline can be further aminated by introducing additional amino groups to the molecule. This can be done through various amination reactions, such as reductive amination or nucleophilic aromatic substitution.
Substitution Reactions: The aromatic ring in the furan moiety can undergo electrophilic aromatic substitution reactions. For example, it can react with electrophilic reagents like nitric acid or acyl halides to form substituted products.
Reductive Reactions: The furan ring can be reduced to tetrahydrofuran under certain conditions, such as with reducing agents like sodium borohydride.
Oxidation: Under oxidative conditions, the furan ring can be oxidized to form furan-2-carboxylic acid or other oxidized products.
Condensation Reactions: N-(furan-2-ylmethyl)aniline can participate in condensation reactions, such as Mannich reactions or various other multicomponent reactions, to form more complex compounds.
Heterocycle Formation: The furan ring can participate in reactions to form other heterocyclic compounds through cyclization reactions.
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4-Fluoro-N-(furan-2-ylmethyl)-2-methylaniline
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N-(Furan-2-ylmethyl)-3,4-dimethylaniline
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