Home Chemistry Organic Building Blocks Thioureas 1,3-Diphenylthiourea
Hydrolysis: 1,3-diphenylthiourea can undergo hydrolysis in the presence of an acid or a base. In acidic conditions, it can be hydrolyzed to produce phenyl isothiocyanate and phenylthiourea. In basic conditions, it can be hydrolyzed to produce phenyl isocyanate and phenylthiourea.
Oxidation: 1,3-diphenylthiourea can be oxidized to form various products. For example, it can be oxidized to form 1,3-diphenylurea or other oxidation products, depending on the reagents and conditions.
Reaction with Electrophiles: 1,3-diphenylthiourea can react with electrophiles to form addition products. For example, it can react with alkyl halides or acyl halides to form addition products. The specific product formed will depend on the electrophile used.
Reaction with Nucleophiles: It can also react with nucleophiles under suitable conditions. For instance, it can undergo nucleophilic addition reactions with amines to produce various products.
Metal Complexation: 1,3-diphenylthiourea can form complexes with metal ions, such as copper, nickel, or zinc. These metal complexes can have various properties and applications in coordination chemistry.
Cross-Coupling Reactions: It can be used in cross-coupling reactions, such as Suzuki-Miyaura coupling or Stille coupling, to form carbon-carbon or carbon-heteroatom bonds when appropriately functionalized.
Other Reactions: Depending on the specific conditions and reagents used, 1,3-diphenylthiourea may participate in a range of other reactions, such as substitution reactions, addition reactions, and rearrangements.
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1,3-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea
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1,3-Bis[4-(trifluoromethyl)phenyl]thiourea
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