Home Chemistry Heterocyclic Building Blocks Pyrrolidines 2,5-Dioxopyrrolidin-1-Yl ((Benzyloxy)Carbonyl)Glycinate
Hydrolysis: The compound can undergo hydrolysis in acidic or basic conditions to break the ester bond, yielding the corresponding carboxylic acid and alcohol. In the case of 2,5-dioxopyrrolidin-1-yl ((benzyloxy)carbonyl)glycinate, this would result in the liberation of glycine and benzyloxyacetic acid.
Aminolysis: The compound can react with amines to form amides. For example, if you treat it with an amine, you can get an amide of the glycinate.
Deprotection of Benzyloxycarbonyl (CBz) Group: The benzyloxycarbonyl (CBz) protecting group can be removed using acid, typically strong acid like hydrogen chloride (HCl) or trifluoroacetic acid (TFA). This would yield the glycinate compound.
Esterification: The carboxylic acid functionality can be esterified with alcohols or acid chlorides to form different esters.
Reduction: The carbonyl groups (both the amide and ester carbonyl) can be reduced to their corresponding alcohols using reducing agents such as lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Cyclization: Depending on the reaction conditions and reagents, this compound may undergo cyclization reactions to form cyclic compounds.
Substitution Reactions: The compound may undergo substitution reactions with nucleophiles, depending on the reaction conditions.
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