Home Chemistry Organic Building Blocks Iodides 4-Bromo-2-Iodoaniline
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —I,—NH2,—Br).
Metalation Reactions: Iodobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Coupling Reactions: Aniline can participate in coupling reactions, such as Ullmann coupling, Buchwald-Hartwig coupling, and others, to form C-N bonds with various partner molecules.
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
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4-Bromo-2-iodo-5-(trifluoromethyl)aniline
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