Home Chemistry Heterocyclic Building Blocks Pyridines 3-Phenoxypyridine
Arylation: 3-Phenoxypyridine can undergo various arylation reactions, where the phenyl group can be further modified or substituted with other aryl groups.
Nucleophilic Substitution: The oxygen atom in the phenoxypyridine ring can act as a nucleophilic site and undergo substitution reactions with electrophiles. For example, it can react with alkyl halides or acyl halides to replace the oxygen atom with the respective group.
Reductive Coupling: 3-Phenoxypyridine can be used in reductive coupling reactions to form C-C bonds. This is often achieved with the use of strong reducing agents and suitable catalysts.
Oxidation: The pyridine ring in 3-phenoxypyridine can be oxidized to various oxidation states under appropriate conditions, such as using strong oxidizing agents.
Grignard Reaction: The compound can react with Grignard reagents to form a variety of products depending on the specific Grignard reagent and reaction conditions.
Halogenation: The pyridine ring can be halogenated at various positions using halogenating reagents like chlorine or bromine.
Metalation: The pyridine ring can be metalated with strong bases like n-butyllithium or organolithium reagents, leading to the formation of organometallic compounds.
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3-Chloro-4-((6-methylpyridin-3-yl)oxy)aniline
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