Home Chemistry Organic Building Blocks Nitroes 1,2-Dimethyl-3-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —NO2,—CH3).
Sulfonation: Nitrobenzene can be sulfonated to introduce a sulfonic acid group (-SO3H) onto the benzene ring. Sulfonation is carried out using concentrated sulfuric acid, which leads to the substitution of one of the hydrogen atoms on the ring.
Alkylation: Similar to acylation, toluene can also undergo Friedel-Crafts alkylation reactions, where an alkyl group is introduced onto the benzene ring. Alkylation reactions also require a Lewis acid catalyst.
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