Home Chemistry Heterocyclic Building Blocks Pyridines 3-(Trifluoromethyl)Pyridine
Substitution Reactions: The trifluoromethyl group can be substituted with other functional groups or atoms, such as alkyl, aryl, or halide groups.
Metalation Reactions: The pyridine ring can undergo metalation reactions with strong bases or organometallic reagents, leading to the formation of metal complexes.
Functional Group Transformations: Various functional groups can be introduced onto the pyridine ring or the trifluoromethyl group through appropriate reactions, such as oxidation, reduction, or addition reactions.
Catalytic Reactions: 3-(trifluoromethyl)pyridine can participate in various catalytic reactions, including cross-coupling reactions, hydrogenation reactions, and other transformations where the trifluoromethyl group or the pyridine ring acts as a catalyst or ligand.
Nucleophilic Aromatic Substitution (SNAr): Depending on the reaction conditions, nucleophilic substitution reactions can occur at the pyridine ring, with the trifluoromethyl group influencing the reactivity and selectivity of the reaction.
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4-Bromo-3-(trifluoromethyl)pyridine hydrobromide
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4-(Chloromethyl)-3-(trifluoromethyl)pyridine hydrochloride
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3-(Trifluoromethyl)isonicotinaldehyde
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(3-(Trifluoromethyl)pyridin-4-yl)methanol
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(3-(Trifluoromethyl)pyridin-4-yl)boronic acid
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3-(Trifluoromethyl)pyridine-4-carboxylic acid
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Methyl 3-hydroxy-5-(trifluoromethyl)picolinate
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N2,N2-Dimethyl-5-(trifluoromethyl)pyridine-2,3-diamine
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5-Amino-3-(trifluoromethyl)picolinonitrile
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1-(3-Methoxy-5-(trifluoromethyl)pyridin-2-yl)ethanone
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5-(Trifluoromethyl)pyridine-3-carboxylic acid
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5-Nitro-3-trifluoromethylpyridine-2-carbonitrile
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5-Nitro-3-(trifluoromethyl)pyridin-2-amine
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2-Methyl-5-nitro-3-(trifluoromethyl)pyridine
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Ethyl 2-cyano-5-(trifluoromethyl)nicotinate
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tert-Butyl (5-(trifluoromethyl)pyridin-3-yl)carbamate
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(5-(Trifluoromethyl)pyridin-2-yl)boronic acid
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