Home Chemistry Organic Building Blocks Trifluoromethyls 1-Fluoro-4-(Trifluoromethoxy)Benzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OCF3).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Grignard Reactions: Trifluoromethoxybenzene can react with Grignard reagents to form new carbon-carbon bonds. This is often used to introduce alkyl or aryl groups onto the benzene ring.
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2-Fluoro-5-(trifluoromethoxy)benzonitrile
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2-Fluoro-5-(trifluoromethoxy)benzoic acid
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(2-Fluoro-5-(trifluoromethoxy)phenyl)boronic acid
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1-Fluoro-2-nitro-4-(trifluoromethoxy)benzene
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4-Fluoro-2-nitro-1-(trifluoromethoxy)benzene
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2,4-Difluoro-5-(trifluoromethoxy)aniline
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2-Fluoro-5-(trifluoromethoxy)phenylacetic acid
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5-Fluoro-2-(trifluoromethoxy)benzoic acid
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2-Bromo-4-fluoro-1-(trifluoromethoxy)benzene
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