Home Chemistry Organic Building Blocks Fluorinated Building Blocks 1-Fluoro-2-Isopropoxybenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OCH(CH3)CH3).
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
Acid-Catalyzed Cleavage: Under acidic conditions, isopropoxybenzene can undergo cleavage of the ether bond to form the corresponding 【alcohol|https://www.ambeed.com/alcohols.html】 and 【phenol|https://www.ambeed.com/phenols.html】. This reaction is known as hydrolysis.
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(2-Fluoro-3-isopropoxy-5-methylphenyl)boronic acid
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(2,6-Difluoro-3-isopropoxyphenyl)boronic acid
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2,4-Difluoro-3-isopropoxyphenylboronic acid
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(2-Fluoro-3-isopropoxyphenyl)boronic acid
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(3-Chloro-5-fluoro-4-isopropoxyphenyl)boronic acid
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5-Bromo-1,3-difluoro-2-isopropoxybenzene
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(3-Chloro-4-fluoro-5-isopropoxyphenyl)boronic acid
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(2,3-Difluoro-4-isopropoxyphenyl)boronic acid
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5-Bromo-1-chloro-3-fluoro-2-isopropoxybenzene
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