Home Chemistry Heterocyclic Building Blocks Tetrahydroquinolines 2,3-Dihydroquinolin-4(1H)-One
Nucleophilic Substitution: The benzyl group can undergo nucleophilic substitution reactions, such as SN1 or SN2 reactions. For example, you can replace the benzyl group with another nucleophile under appropriate conditions.
Acylation: 1-Benzyl-1H-1,2,3-triazole can undergo acylation reactions, where an acyl group is introduced onto the triazole ring. This can be achieved using acylating agents like acyl chlorides or anhydrides.
Alkylation: Similar to acylation, alkylation reactions involve the introduction of alkyl groups onto the triazole ring. Alkyl halides or alkyl sulfonates can be used for this purpose.
Reduction: The benzyl group or the triazole ring itself can be reduced using appropriate reducing agents to convert them to different compounds.
Oxidation: Oxidation reactions can be used to modify the benzyl or triazole group, leading to the formation of various oxidation products.
Click Chemistry: Triazoles are commonly used in click chemistry reactions, such as the Huisgen 1,3-dipolar cycloaddition, which involves the reaction of azides and alkynes to form 1,2,3-triazoles.
Nitrilation: The nitrogen atoms in the triazole ring can be nitrated to introduce nitro groups.
Substitution Reactions: The nitrogen atoms in the triazole ring can undergo substitution reactions with various nucleophiles or electrophiles, leading to the formation of substituted triazoles.
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8-Methyl-1,2,3,4-tetrahydroquinolin-4-one
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7-Fluoro-2,3-dihydroquinolin-4(1H)-one
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6,8-Difluoro-2,3-dihydroquinolin-4(1H)-one
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1,6-Dimethyl-2,3-dihydroquinolin-4(1H)-one
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5-Bromo-2,3-dihydroquinolin-4(1H)-one
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