Home Chemistry Organic Building Blocks Aryls N-Benzylbenzamide
Reductive Amination: N-Benzylbenzamide can be subjected to reductive amination reactions, where the carbonyl group is reduced and replaced with an amine group, resulting in the formation of secondary or tertiary amines.
Friedel-Crafts Acylation: N-Benzylbenzamide can be used as an acylating agent in Friedel-Crafts acylation reactions with arenes or other nucleophiles to form various acylated products.
Amide Bond Cleavage: Under certain conditions, N-benzylbenzamide can undergo amide bond cleavage, leading to the formation of benzoic acid and an amine.
Reduction: N-Benzylbenzamide can be reduced to N-benzylbenzylamine using reducing agents such as lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Nucleophilic Substitution: The carbonyl group in N-benzylbenzamide can undergo nucleophilic substitution reactions with nucleophiles, such as Grignard reagents or organolithium compounds, to form various products.
Oxidation: N-Benzylbenzamide can be oxidized under appropriate conditions to yield different products, depending on the choice of oxidizing agent and reaction conditions.
Amide Formation: N-Benzylbenzamide can be used as a starting material for the synthesis of secondary or tertiary amides through amide bond-forming reactions.
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(4-(Benzylcarbamoyl)-3-fluorophenyl)boronic acid
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