Home Chemistry Heterocyclic Building Blocks Indazoles 1H-Indazol-6-Ol
Substitution Reactions: The hydroxyl group can undergo substitution reactions with various electrophiles, leading to the formation of ether, ester, or other functionalized derivatives.
Oxidation: The alcohol group can be oxidized to form the corresponding aldehyde, ketone, or carboxylic acid under appropriate conditions.
Reduction: The alcohol group can be reduced to the corresponding alkane using reducing agents such as lithium aluminum hydride or sodium borohydride.
Acylation: The hydroxyl group can react with acyl chlorides or acid anhydrides to form esters or amides.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Ring-closure Reactions: The indazole ring can undergo ring-closure reactions to form heterocyclic compounds under certain conditions.
Protonation: The alcohol group can be protonated under acidic conditions to form the corresponding oxonium ion.
Dehydration: Under appropriate conditions, dehydration reactions can occur to eliminate water and form unsaturated compounds.
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