Home Chemistry Heterocyclic Building Blocks Piperidines Methyl Piperidine-2-Carboxylate
Ester Hydrolysis: Methyl piperidine-2-carboxylate can undergo hydrolysis in the presence of an acid or base to form 【piperidine-2-carboxylic acid and methanol.
Nucleophilic Substitution: The ester group can undergo nucleophilic substitution reactions with various nucleophiles, leading to the formation of substituted esters or other functionalized derivatives.
Reduction: The carbonyl group of the ester can be reduced to the corresponding alcohols using reducing agents such as lithium aluminum hydride or sodium borohydride.
Decarboxylation: Under certain conditions, such as heating or treatment with specific reagents, decarboxylation may occur, leading to the loss of the carboxyl group and formation of the corresponding amine.
Acylation: The nitrogen atom in the piperidine ring can undergo acylation reactions to form N-acyl derivatives.
Ring-opening Reactions: The piperidine ring may undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Esterification: Methyl piperidine-2-carboxylate can react with carboxylic acids or acid derivatives to form esters through esterification reactions.
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1-tert-Butyl 2-methyl 4-hydroxypiperidine-1,2-dicarboxylate
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1-tert-Butyl 2-methyl piperidine-1,2-dicarboxylate
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1-tert-Butyl 2-methyl (2R,4S)-4-hydroxypiperidine-1,2-dicarboxylate
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Methyl 4-hydroxypiperidine-2-carboxylate hydrochloride
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(2S,5S)-1-tert-Butyl 2-methyl 5-hydroxypiperidine-1,2-dicarboxylate
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(R)-1-tert-Butyl 2-methyl piperidine-1,2-dicarboxylate
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