Chemistry Heterocyclic Building Blocks Oxazolines (R)-4-Phenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole

(R)-4-Phenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole

Substitution Reactions: Depending on the reaction conditions, you may see substitution reactions at various positions within the molecule, involving nucleophiles or electrophiles. For example, nucleophilic aromatic substitution or electrophilic aromatic substitution reactions could occur. Heterocycle Transformations: Reactions that modify the oxazole or pyridine rings can take place. These might include ring-opening reactions or ring-closing reactions, depending on the reagents and conditions. Oxidation/Reduction Reactions: Oxidation or reduction reactions may be carried out to change the oxidation state of the compound. For instance, you can perform reductions using reducing agents like LiAlH4 or Pd/C, or oxidations using reagents like potassium permanganate (KMnO4) or chromium(VI) reagents. Cross-Coupling Reactions: You can perform cross-coupling reactions to introduce new substituents at specific positions in the molecule. For example, Suzuki-Miyaura, Heck, or Stille reactions can be employed with appropriate partners. Functional Group Transformations: The phenyl group and the pyridine group can undergo various functional group transformations, such as acylation, alkylation, or deprotonation reactions. Chirality Control: Since the compound is chiral, you can perform reactions to control or alter its stereochemistry. Enantioselective reactions can be used to synthesize specific enantiomers of the compound. Rearrangements: Depending on the conditions, rearrangement reactions might occur, leading to different structural isomers.

Further Reading:

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(3Ar,8As)-2-(Pyridin-2-Yl)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole (3As,8Ar)-2-(Pyridin-2-Yl)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole (4R,5S)-4,5-Diphenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (R)-4-Benzyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (R)-4-Phenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-(Tert-Butyl)-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-Benzyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-Isopropyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-Phenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole 1,3-Bis(4,5-Dihydrooxazol-2-Yl)Benzene 2,2'-(1,3-Diphenylpropane-2,2-Diyl)Bis(4,5-Dihydrooxazole) 2,2'-(2-Phenylethane-1,1-Diyl)Bis(4,5-Dihydrooxazole) 2,3-Dihydropyrazolo[5,1-B]Oxazole 2,6-Bis(4,5-Dihydrooxazol-2-Yl)Pyridine 2-(6-Benzhydrylpyridin-2-Yl)-4,5-Dihydrooxazole 2-(6-Cyclopropylpyridin-2-Yl)-4,5-Dihydrooxazole 2-(Benzo[B]Thiophen-2-Yl)-4,5-Dihydrooxazole 2-(Pyridin-2-Ylmethyl)-4,5-Dihydrooxazole 2-(Quinolin-2-Yl)-4,5-Dihydrooxazole 2-Phenyl-4,5-Dihydrooxazole 4,4',5,5'-Tetrahydro-2,2'-Bioxazole 4-(Tert-Butyl)-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole 4-Isopropyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole Bis((3Ar,8As)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazol-2-Yl)Methane Bis((3As,8Ar)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazol-2-Yl)Methane Bis(4,5-Dihydrooxazol-2-Yl)Methane

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