Home Chemistry Heterocyclic Building Blocks Piperazines 1-Benzhydrylpiperazine
N-Alkylation: You can alkylate the nitrogen atoms in the piperazine ring to introduce various substituents. This can be done using alkylating agents like alkyl halides or sulfonyl chlorides. N-alkylation can be a useful strategy to modify the compound's properties.
Amidation: You can react 1-benzhydrylpiperazine with acyl chlorides or anhydrides to form amides. This reaction is a common way to introduce amide functional groups into the molecule.
Esterification: 1-Benzhydrylpiperazine can undergo esterification with carboxylic acids and acid chlorides to form esters. Esterification is a common reaction for modifying the compound's chemical structure.
Heterocyclic Chemistry: 1-Benzhydrylpiperazine contains a piperazine ring, which is a heterocyclic ring. You can perform various reactions involving the piperazine ring, such as ring opening reactions, ring closures, and substitutions.
Reductive Amination: You can perform reductive amination by reacting 1-benzhydrylpiperazine with aldehydes or ketones in the presence of reducing agents. This can be used to introduce different amine groups into the molecule.
Halogenation: You can introduce halogen atoms (e.g., chlorine or bromine) into the molecule by using halogenating agents like thionyl chloride or phosphorus tribromide.
Oxidation/Reduction: Depending on the reaction conditions, you can oxidize or reduce specific functional groups within the molecule.
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