Home Chemistry Organic Building Blocks Bromides 2-Bromo-5-Fluorobenzoic Acid
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—COOH,—F).
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
Esterification: Benzoic acid can undergo esterification reactions with 【alcohols|https://www.ambeed.com/alcohols.html】 in the presence of a catalyst, typically an acid catalyst like sulfuric acid. This reaction leads to the formation of benzoate 【esters|https://www.ambeed.com/esters.html】 and water.
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
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