Home Chemistry Organic Building Blocks Bromides 2-Bromo-6-Chloroaniline
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—NH2,—Cl).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Coupling Reactions: Aniline can participate in coupling reactions, such as Ullmann coupling, Buchwald-Hartwig coupling, and others, to form C-N bonds with various partner molecules.
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
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Methyl 4-amino-3-bromo-5-chlorobenzoate
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2-Bromo-6-chloro-4-(trifluoromethoxy)aniline
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3-Amino-4-bromo-2,6-dichlorobenzoic acid
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2-Bromo-6-Chloro-4-(trifluoromethyl)aniline
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