Home Chemistry Heterocyclic Building Blocks Pyridines Pyridin-2-Ol
Acid-Base Reactions: Like other alcohols, pyridin-2-ol can undergo acid-base reactions, where it can act as a base by accepting a proton from an acid or as an acid by donating a proton to a base.
Substitution Reactions: The hydroxyl group can undergo substitution reactions, where it can be replaced by another functional group. For example, it can undergo esterification to form esters or ether formation reactions.
Oxidation Reactions: Pyridin-2-ol can be oxidized to form various products depending on the conditions. Under mild conditions, it can be oxidized to form pyridine-2,3-dione (succinimide), while under harsher conditions, it can be further oxidized to form pyridine-2,5-dicarboxylic acid.
Nucleophilic Substitution: The nitrogen atom in the pyridine ring can undergo nucleophilic substitution reactions, where it can react with electrophiles to form substituted products.
Metal Complexation: Pyridin-2-ol can act as a ligand to form coordination complexes with transition metal ions, typically through the oxygen atom of the hydroxyl group.
Condensation Reactions: Pyridin-2-ol can undergo condensation reactions with carbonyl compounds or other nucleophiles to form various heterocyclic compounds.
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