Home Chemistry Organic Building Blocks Bromides 4-Bromo-3-Fluoroaniline
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—F,—NH2).
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
Reimer-Tiemann Reaction: Aniline can react with chloroform (CHCl3) and a base to undergo the Reimer-Tiemann reaction, leading to the formation of a salicylaldehyde derivative.
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5-Bromo-4-fluoro-N1-methylbenzene-1,2-diamine
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Methyl 5-amino-2-bromo-3-fluorobenzoate
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