Home Chemistry Heterocyclic Building Blocks Other Aliphatic Heterocycles 1,4-Diazepane
Ring Opening: 1,4-diazepane can undergo ring-opening reactions under various conditions. For example, treatment with acid or base can lead to the cleavage of the ring, producing different products.
Acylation: 1,4-diazepane can be acylated by reacting it with acylating agents such as acyl chlorides or anhydrides. This can lead to the formation of amides.
Alkylation: You can alkylate 1,4-diazepane using alkyl halides or similar reagents to introduce alkyl groups onto the nitrogen atoms. This can lead to the formation of quaternary ammonium compounds.
Reduction: 1,4-diazepane can be reduced to its corresponding tetrahydro derivative using reducing agents such as hydrogen and a metal catalyst.
Oxidation: It can be oxidized under certain conditions to form various oxidation products.
Condensation Reactions: 1,4-diazepane can participate in condensation reactions, such as the formation of imines or iminium ions when reacted with carbonyl compounds.
Substitution Reactions: Depending on the reaction conditions and reagents, various substitution reactions can occur, leading to the functionalization of the molecule.
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(R)-tert-Butyl 3-methyl-1,4-diazepane-1-carboxylate
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1-(tert-Butoxycarbonyl)-1,4-diazepane-5-carboxylic acid
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(S)-tert-Butyl 2-methyl-1,4-diazepane-1-carboxylate
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(S)-tert-Butyl 3-methyl-1,4-diazepane-1-carboxylate
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(R)-tert-Butyl 7-methyl-1,4-diazepane-1-carboxylate
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