Home Chemistry Organic Building Blocks Trifluoromethyls 3-(Trifluoromethyl)Benzoic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —CF3,—COOH).
Friedel-Crafts Acylation/Alkylation: The (trifluoromethyl)benzene can undergo Friedel-Crafts acylation or alkylation reactions, in which an acyl or alkyl group is added to the benzene ring. These reactions are catalyzed by Lewis acids and result in the formation of new carbon-carbon bonds.
Decarboxylation: Under certain conditions, benzoic acid can undergo decarboxylation, where it loses a carbon dioxide molecule from its carboxylic acid group. This reaction usually requires high temperatures and is often observed in the presence of strong acids or bases.
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2,5-Bis(trifluoromethyl)terephthalic acid
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2-Methoxy-5-(trifluoromethyl)benzoic acid
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6-Bromo-2-fluoro-3-(trifluoromethyl)benzoic acid
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4-Hydroxy-3-(trifluoromethyl)benzoic acid
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2-Chloro-3-(trifluoromethyl)benzoic acid
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3-Cyano-5-(trifluoromethyl)benzoic Acid
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2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid
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4-Chloro-3,5-bis(trifluoromethyl)benzoic acid
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4-Isopropoxy-3-(trifluoromethyl)benzoic acid
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4-Borono-3-(trifluoromethyl)benzoic acid
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