Chemistry Organic Building Blocks Aryls Cyclopentylbenzene

Cyclopentylbenzene

Aromatic Substitution: The benzene ring in cyclopentylbenzene is susceptible to electrophilic aromatic substitution reactions, such as nitration, sulfonation, halogenation, and Friedel-Crafts reactions. For example, you can nitrate cyclopentylbenzene to produce nitrocyclopentylbenzene. Hydrogenation: Cyclopentylbenzene can undergo catalytic hydrogenation to reduce the benzene ring and convert it into cyclopentylcyclohexane. This reaction involves the addition of hydrogen gas H2 in the presence of a catalyst, such as platinum or palladium. Oxidation: The alkyl side chain (cyclopentyl group) can be oxidized to form a carboxylic acid. Common reagents for this reaction include potassium permanganate (KMnO4) or chromic acid (H2CrO4). Halogenation of the Alkyl Group: The cyclopentyl group can be halogenated using halogenating agents like bromine (Br2) or chlorine (Cl2) to produce halocyclopentylbenzenes. Dehydrogenation: Under certain conditions, cyclopentylbenzene can undergo dehydrogenation to form cyclopentadiene and benzene. This reaction is often carried out at elevated temperatures. Friedel-Crafts Acylation/Alkylation: The benzene ring in cyclopentylbenzene can be acylated or alkylated using Friedel-Crafts reactions. This involves the use of a Lewis acid catalyst, such as aluminum chloride (AlCl3), along with an acylating agent or alkylating agent. Reduction of the Benzene Ring: Under certain conditions, such as treatment with strong reducing agents, the benzene ring can be reduced to form a cyclohexane ring. Grignard Reaction: Cyclopentylbenzene can react with a Grignard reagent, such as an alkyl or aryl magnesium halide, to form a substituted cyclopentylbenzene compound.

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((2s,6s)-6-phenoxytetrahydro-2h-pyran-2-yl)methanol (2s,4s)-2-phenoxytetrahydro-2h-pyran-4-yl acetate (6-phenoxytetrahydro-2h-pyran-2-yl)methanol (8s,9s,14r)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3h-cyclopenta[a]phenanthren-3-one (8s,9s,14r)-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta[a]phenanthrene (9h-fluoren-9-yl)methyl (2-(tritylthio)ethyl)carbamate (9h-fluoren-9-yl)methyl cyclohexylcarbamate (benzylsulfonyl)benzene (cyclopentyloxy)benzene (e)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one (e)-3-styrylphenol 1,1-dimethylcyclopropane 1,2-bis(diphenylphosphaneyl)ethane 1,3,4,5-tetrahydro-2h-benzo[b]azepin-2-one 1,3-diphenylurea 1-(2-hydroxyphenyl)-2-phenylethan-1-one 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 1-([1,1'-biphenyl]-4-yl)ethan-1-one 1-(naphthalen-2-yl)ethan-1-one 1-benzyl-4-chlorobenzene 1-benzyl-4-fluorobenzene 1-bromonaphthalene 1-chloronaphthalene 1-fluoronaphthalene 1-methoxynaphthalene 1-methyl-4-(phenylethynyl)benzene 1-methylnaphthalene 1-naphthaldehyde 1-naphthoic acid 1-nitronaphthalene 10h-phenothiazine 2,2',3,3',5,5',6,6'-octafluoro-1,1'-biphenyl 2,5-diphenylthiophene 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2-(trifluoromethyl)-1,1'-biphenyl 2-benzylaniline 2-bromo-1,1'-biphenyl 2-bromonaphthalene 2-chloro-1,1'-biphenyl 2-chloronaphthalene 2-ethoxynaphthalene 2-fluorocyclopropane-1-carboxylic acid 2-hydroxycyclohexa-2,5-diene-1,4-dione 2-iodonaphthalene 2-methoxy-1,1'-biphenyl 2-methoxynaphthalene 2-methoxytetrahydro-2h-pyran 2-methyl-1,1'-biphenyl 2-methylnaphthalene 2-naphthaldehyde 2-naphthoic acid 2-naphthonitrile 2-nitronaphthalene 2-phenoxytetrahydro-2h-pyran-4-yl acetate 2-phenylnaphthalene 3,3'-diphenyl-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene 3,3-diphenyl-3h-benzo[c][1,2]oxathiole 1,1-dioxide 3-bromo-1,1'-biphenyl 3-chloro-1,1'-biphenyl 3-fluoro-1,1'-biphenyl 3-methyl-1,1'-biphenyl 3-methyl-1,1':4',1''-terphenyl 3-phenethylphenol 3-phenyl-1,2,4,5-tetrazine 3-styrylphenol 4-(bromomethyl)-1,1'-biphenyl 4-(phenyldiazenyl)benzoic acid 4-(phenylsulfonyl)morpholine 4-(tert-butyl)-1,1'-biphenyl 4-cyclohexylphenol 4-iodo-1,1'-biphenyl 4-methoxy-1,1'-biphenyl 9h-xanthene [1,1'-biphenyl]-2-amine [1,1'-biphenyl]-2-carbonitrile [1,1'-biphenyl]-2-carboxylic acid [1,1'-biphenyl]-2-ol [1,1'-biphenyl]-3-amine [1,1'-biphenyl]-3-carbaldehyde [1,1'-biphenyl]-3-carboxylic acid [1,1'-biphenyl]-3-ol [1,1'-biphenyl]-4-carbaldehyde [1,1'-biphenyl]-4-carbonitrile [1,1'-biphenyl]-4-ol [1,1'-biphenyl]-4-ylboronic acid Benzyltriphenylphosphonium Cyclopentylbenzene Cyclopropanecarboxylic acid Cyclopropyl(phenyl)methanamine Cyclopropyl(phenyl)methanone Diphenyl phosphonate Diphenylphosphane Diphenylphosphine oxide Ethane-1,1-diyldibenzene Ethene-1,1,2-triyltribenzene Ethyl cyclopropanecarboxylate Methyl 1-naphthoate Methyl 2-naphthoate Methyl [1,1'-biphenyl]-4-carboxylate Methyl cyclopropanecarboxylate N,1-diphenylmethanimine N,n-dimethylnaphthalen-1-amine N-((5r,6r)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-6-yl)-2-phenylacetamide N-benzylbenzamide N-benzylbenzenesulfonamide N-cyclopropylbenzamide N-cyclopropylbenzenesulfonamide N-phenethylbenzamide N-phenyl-2-naphthamide Naphthalen-1-ol Naphthalen-1-ylboronic acid Naphthalen-1-ylmethanol Naphthalen-2-amine Naphthalen-2-ol Naphthalen-2-ylboronic acid Naphthalene-1,4-diol Naphthalene-2-sulfonic acid Propane-2,2-diyldibenzene Tert-butyl cyclopropylcarbamate Tetrahydro-2h-pyran-2-ol Tetrahydro-2h-pyran-2-yl acetate Tetraphenylmethane Triphenylene Vinylcyclopropane

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