Home Chemistry Organic Building Blocks Trifluoromethyls 2-(Trifluoromethoxy)Benzonitrile
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —OCF3,—C≡N).
Nucleophilic Aromatic Substitution (NAS): In some cases, under appropriate conditions, nucleophiles can attack the benzene ring, leading to nucleophilic aromatic substitution reactions. The trifluoromethoxy group can influence the reactivity of the ring.
Cyanation and Cyanation Reactions: The cyano group in benzonitrile can serve as a nucleophile in various reactions, leading to the introduction of cyano groups onto other molecules.
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4-Bromo-2-(trifluoromethoxy)benzonitrile
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5-Bromo-2-(trifluoromethoxy)benzonitrile
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4-Hydroxy-2-(trifluoromethoxy)benzonitrile
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4-Methoxy-2-(trifluoromethoxy)benzonitrile
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2-Chloro-6-(trifluoromethoxy)benzonitrile
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