Chemistry Heterocyclic Building Blocks Thiophenes 2-(Thiophen-2-Yl)Pyridine

2-(Thiophen-2-Yl)Pyridine

Arylation or Alkylation: You can introduce substituents to the pyridine ring through electrophilic aromatic substitution. For example, you can react 2-(thiophen-2-yl)pyridine with aryl or alkyl halides in the presence of a suitable base or transition metal catalyst to add substituents to the pyridine ring. Halogenation: 2-(thiophen-2-yl)pyridine can undergo halogenation reactions with halogenating agents like bromine or chlorine to introduce halogen atoms to the molecule. Reduction: Reduction of the pyridine or thiophene ring can be achieved with reducing agents like hydrogen gas (catalytic hydrogenation) or with chemical reducing agents like lithium aluminum hydride (LiAlH4). Oxidation: Oxidation of 2-(thiophen-2-yl)pyridine can be carried out with various oxidizing agents to convert it to the corresponding oxidation product. Grignard Reaction: 2-(thiophen-2-yl)pyridine can react with Grignard reagents, which are organomagnesium compounds, to form new carbon-carbon bonds and introduce various functional groups. Cross-Coupling Reactions: It can participate in various cross-coupling reactions like Suzuki-Miyaura, Heck, or Sonogashira reactions to form C-C bonds with other organic compounds. Substitution Reactions: 2-(thiophen-2-yl)pyridine can undergo nucleophilic substitution reactions, especially with electrophilic functional groups.

Further Reading:

Framework+−

(9H-Fluoren-9-Yl)Methyl (2-(Thiophen-2-Yl)Ethyl)Carbamate 1-(Thiophen-2-Yl)Ethan-1-One 2,2'-Bithiophene 2,2':5',2''-Terthiophene 2,3-Dihydrothieno[3,4-B][1,4]Dioxine 2,5-Dibromothiophene 2,5-Diphenylthiophene 2-(Thiophen-2-Yl)Pyridine 2-(Trifluoromethyl)Thiophene 2-Chlorothiophene 2-Ethynylthiophene 2-Iodothiophene 2-Methoxythiophene 2-Nitrothiophene 3-Bromothiophene 3-Chlorothiophene 3-Fluorothiophene 3-Methoxythiophene 3-Methylthiophene 3-Nitrothiophene 3-Phenylthiophene 4,4,5,5-Tetramethyl-2-(Thiophen-2-Yl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(Thiophen-3-Yl)-1,3,2-Dioxaborolane 4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine 4,5,6,7-Tetrahydrothieno[3,2-C]Pyridine 4,7-Di(Thiophen-2-Yl)Benzo[C][1,2,5]Thiadiazole 4,8-Di(Thiophen-2-Yl)Benzo[1,2-B:4,5-B']Dithiophene 4-Phenyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepine 4H-Cyclopenta[2,1-B:3,4-B']Dithiophene 4H-Thieno[3,2-B]Pyrrole 4H-Thieno[3,4-C]Pyrrole-4,6(5H)-Dione 5,6-Dihydro-4H-Cyclopenta[B]Thiophene 5-(Thiophen-2-Yl)Isoxazole 5-Benzyl-4,5,6,7-Tetrahydrothieno[3,2-C]Pyridine 5-Phenylthiophen-2-Amine Benzo[1,2-B:4,5-B']Dithiophene Dibenzo[B,D]Thiophene Dihydrothiophen-3(2H)-One Dithieno[3,2-B:2',3'-D]Thiophene Ethyl Thiophene-2-Carboxylate Ethyl Thiophene-3-Carboxylate Methyl Thiophene-3-Carboxylate N,N-Diphenyl-4-(Thiophen-2-Yl)Aniline Phenyl(Thiophen-2-Yl)Methanone Thieno[2,3-B]Pyridine Thieno[2,3-C]Pyridine Thieno[2,3-D]Pyrimidine Thieno[3,2-B]Pyridine Thieno[3,2-B]Thiophene Thieno[3,2-C]Pyridine Thieno[3,2-D]Pyrimidine Thieno[3,4-B]Thiophene Thiophen-2-Ylboronic Acid Thiophen-2-Ylmethanol Thiophen-3-Amine Thiophen-3-Ol Thiophene-2-Carbaldehyde Thiophene-2-Carbonitrile Thiophene-3-Carbaldehyde Thiophene-3-Carbonitrile Thiophene-3-Carboxamide Thiophene-3-Carboxylic Acid

By Key Group+−

Acetylthiophene Aminothiophene Bromothieno Chlorothieno Chlorothiophene Cyanothiophene Dibromothieno Dibromothiophene Dichlorothieno Dichlorothiophene Dihydrothieno Dihydrothiophene Dihydroxythiophene Dimethylthieno Dimethylthiophene Dithiophene Fluorothiophene Formylthiophene Hydroxythiophene Iodothieno Iodothiophene Methylthieno Nitrothiophene Oxotetrahydrothiophene Terthiophene Tetrahydrothieno Thiophen-Amine-Hydrochloride Thiophenecarboxaldehyde Thiphen-Amine-Hydrochloride Trithiophene

By Route Intermediates+−

cLogP+−

H-Acceptors+−

H-Donors+−

Polar Surface Area+−

Druglikeness+−

NNCH/NNH+−

sp3-Atoms+−

Non-Aromatic Rings+−

Aromatic Rings+−

Rotatable Bonds+−

Typically In Stock
Purity
  • Please Select
  • 99+%
  • 99%
  • 98+%
  • 98%
  • 97+%
  • 97%
  • 96+%
  • 96%
  • 95+%
  • 95%
  • 93%
  • 90+%
  • 90%
Size
  • Please Select
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • 500g
  • 1000g
  • 1kg
Clear Filters
2-(Thiophen-2-yl)pyridin-4-amine

click to sign in and save

A10772831020540-64-095%

2-(Thiophen-2-yl)pyridin-4-amine

$335.00/1g

Detail
2-(Thiophen-2-yl)pyridine

click to sign in and save

A5883573319-99-197%

2-(Thiophen-2-yl)pyridine

$12.00/1g

Detail
5-Bromo-2-(5-bromothiophen-2-yl)pyridine

click to sign in and save

A130532136902-53-998% (stabilized with Cu+HQ+MgO)

5-Bromo-2-(5-bromothiophen-2-yl)pyridine

$20.00/100mg

Detail
2-(5-Bromothiophen-2-yl)pyridine

click to sign in and save

A422348123784-07-697% (stabilized with Cu+HQ+MgO)

2-(5-Bromothiophen-2-yl)pyridine

$500.00/25g

Detail
5-Bromo-2-(thiophen-2-yl)pyridine

click to sign in and save

A51653691891-74-698%

5-Bromo-2-(thiophen-2-yl)pyridine

$241.00/1g

Detail
1    page 1 of 1 Pages

Inquiry