Chemistry Heterocyclic Building Blocks Triazoles 4H-1,2,4-Triazole

4H-1,2,4-Triazole

Substitution Reactions: Triazoles can undergo electrophilic aromatic substitution reactions. For example, nitration, halogenation, and alkylation of the aromatic ring can occur. Azide-Alkyne Click Reaction (Huisgen Cycloaddition): 4H-1,2,4-triazoles can participate in the well-known azide-alkyne cycloaddition reaction, often referred to as click chemistry. In this reaction, a triazole ring is formed when an azide and an alkyne react in the presence of a copper catalyst. This reaction is widely used in bioconjugation and materials science. Cyclization Reactions: 4H-1,2,4-triazoles can be used as substrates in various cyclization reactions, forming compounds with multiple heterocyclic rings. Metal-Catalyzed Reactions: Triazoles can be involved in metal-catalyzed reactions, such as the formation of metal complexes, which can have applications in coordination chemistry. Nitrosation Reactions: Triazoles can react with nitrous acid to form diazo compounds, which can further participate in various reactions. Reduction Reactions: Reduction of the triazole ring can be carried out using reducing agents. Nucleophilic Addition: Triazoles can undergo nucleophilic additions at the N-1 position or other positions, depending on the conditions and reagents.

Further Reading:

Framework+−

(5As,10Br)-2-Phenyl-2,5A,6,10B-Tetrahydro-4H-Indeno[2,1-B][1,2,4]Triazolo[4,3-D][1,4]Oxazin-11-Ium 1-(Phenylsulfonyl)-1H-1,2,4-Triazole 1-Benzyl-1H-1,2,3-Triazole 1-Benzyl-1H-1,2,4-Triazole 1-Methyl-1H-1,2,3-Triazole 1-Methyl-1H-1,2,4-Triazole 1-Methyl-1H-Benzo[D][1,2,3]Triazole 1-Phenethyl-1H-1,2,4-Triazole 1-Phenyl-1H-1,2,3-Triazole 1-Phenyl-1H-1,2,4-Triazole 1H-1,2,4-Triazol-3-Amine 1H-1,2,4-Triazol-5-Amine 1H-Benzo[D][1,2,3]Triazol-1-Ol 2-Bromo-[1,2,4]Triazolo[1,5-A]Pyridine 2-Phenyl-2,5,6,7-Tetrahydropyrrolo[2,1-C][1,2,4]Triazol-4-Ium 2-Phenyl-2H-1,2,3-Triazole 2-Phenyl-2H-Benzo[D][1,2,3]Triazole 2H-1,2,3-Triazole 4-(4-Cyclopropylnaphthalen-1-Yl)-4H-1,2,4-Triazole 4-Phenyl-4H-1,2,4-Triazole 4-Phenyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepine 4H-1,2,4-Triazole 5-Bromo-1H-1,2,4-Triazole 5-Bromo-1H-Benzo[D][1,2,3]Triazole 5-Fluoro-1H-Benzo[D][1,2,3]Triazole 6-Bromo-[1,2,4]Triazolo[1,5-A]Pyridine 6-Bromo-[1,2,4]Triazolo[4,3-A]Pyridine 8-Bromo-[1,2,4]Triazolo[1,5-A]Pyridine [1,2,4]Triazolo[1,5-A]Pyrazine [1,2,4]Triazolo[1,5-A]Pyridin-2-Amine [1,2,4]Triazolo[4,3-A]Pyridin-3-Ylmethanamine Ethyl 1H-1,2,4-Triazole-3-Carboxylate

By Key Group+−

Amino-Triazole Amino-Triazolopyrimidine Benzotriazole Benzotriazole-Ethylamine Bromo-Triazole Bromotriazolopyridine Chloro-Triazolopyridazine Chloro-Triazolopyridine Chloro-Triazolopyrimidine Fluoro-Triazolopyridine Indenotriazolooxazine Methyl-Triazole Methyl-Triazolopyridine Methyl-Triazolopyrimidine Nitro-Triazole Phenyl-Triazole Piperidine-Triazole Pyrrolotriazole Triazol-Amine Triazol-Benzene Triazol-One Triazol-Oxazine Triazol-Pyridine Triazole-Carbonitrile Triazole-Carboxylate Triazole-Carboxylic Triazole-Carboxylic-Acid Triazole-Methanol Triazolopyrazine Triazolopyridazine Triazolopyridin-Amine Triazolopyridine Triazolopyridine-Carboxylate Triazolopyridine-Carboxylic Triazolopyrimidine

By Parent Nucleus+−

Aromatic Heterocycles Guanidines Imidazoles Other Aliphatic Heterocycles Other Aromatic Heterocycles Oxadiazoles Piperazines Piperidines Pyridines Pyrimidines Tetrahydrofurans Tetrahydropyrans Thiophenols

By Functional Group+−

Alcohols Aldehydes Alkyls Amides Amines Aryls Benzyl Chlorides Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Hydrazines Iodides Ketones Nitriles Sulfides Sulfonates Sulfones Thiols Trifluoromethyls

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

    Typically In Stock
    Purity
    • Please Select
    • 99+%
    • 99%
    • 98+%
    • 98%
    • 97+%
    • 97%
    • 96+%
    • 96%
    • 95+%
    • 95%
    • 93%
    • 90+%
    • 90%
    Size
    • Please Select
    • 1mg
    • 2mg
    • 5mg
    • 10mg
    • 25mg
    • 50mg
    • 100mg
    • 250mg
    • 1g
    • 5g
    • 10g
    • 25g
    • 100g
    • 500g
    • 1000g
    • 1kg
    Clear Filters
    5-Methyl-4H-1,2,4-triazol-3-amine

    click to sign in and save

    A1582934923-01-798%

    5-Methyl-4H-1,2,4-triazol-3-amine

    $895.00/100g

    Detail
    5-Amino-4H-1,2,4-triazole-3-carboxylic acid

    click to sign in and save

    A1129723641-13-295%

    5-Amino-4H-1,2,4-triazole-3-carboxylic acid

    $153.00/1kg

    Detail
    4H-1,2,4-Triazol-3-amine

    click to sign in and save

    A41731665312-61-095%

    4H-1,2,4-Triazol-3-amine

    $74.00/100g

    Detail
    2-((4H-1,2,4-Triazol-3-yl)thio)acetic acid

    click to sign in and save

    A44375624127-58-097%

    2-((4H-1,2,4-Triazol-3-yl)thio)acetic acid

    $65.00/100mg

    Detail
    4H-1,2,4-Triazole-3-sulfonyl chloride

    click to sign in and save

    A4089316461-29-695%

    4H-1,2,4-Triazole-3-sulfonyl chloride

    $183.00/1g

    Detail
    5-(Trifluoromethyl)-4H-1,2,4-triazole-3-thiol

    click to sign in and save

    A34130268744-64-995%

    5-(Trifluoromethyl)-4H-1,2,4-triazole-3-thiol

    $45.00/100mg

    Detail
    3-Bromo-4H-1,2,4-triazole

    click to sign in and save

    A42680657704-26-498%

    3-Bromo-4H-1,2,4-triazole

    $35.00/1g

    Detail
    3,5-Dimethyl-4H-1,2,4-triazole

    click to sign in and save

    A2137127343-34-297%

    3,5-Dimethyl-4H-1,2,4-triazole

    $160.00/100g

    Detail
    4H-1,2,4-Triazole

    click to sign in and save

    A92081063598-71-095%

    4H-1,2,4-Triazole

    $57.00/5g

    Detail
    5-tert-Butyl-4H-[1,2,4]triazol-3-ylamine

    click to sign in and save

    A289073202403-45-095%

    5-tert-Butyl-4H-[1,2,4]triazol-3-ylamine

    $145.00/250mg

    Detail
    5-Isopropyl-4H-1,2,4-triazol-3-amine

    click to sign in and save

    A18345422882-41-395%

    5-Isopropyl-4H-1,2,4-triazol-3-amine

    $36.00/100mg

    Detail
    5-Methyl-4H-1,2,4-triazol-3-amine hydrochloride

    click to sign in and save

    A24412123350-30-395%

    5-Methyl-4H-1,2,4-triazol-3-amine hydrochloride

    $19.00/1g

    Detail
    1    page 1 of 1 Pages

    Inquiry