Home Chemistry Heterocyclic Building Blocks Morpholines (S)-3-Phenylmorpholine
Acid-Base Reactions: (S)-3-phenylmorpholine can act as both a base and an acid. It can undergo acid-base reactions with strong acids or bases to form salts or protonated/deprotonated species.
Nucleophilic Substitution: The nitrogen atom in the morpholine ring is nucleophilic and can undergo nucleophilic substitution reactions. This could involve the displacement of the phenyl group, or reactions at the morpholine ring.
Acylation: (S)-3-phenylmorpholine can be acylated using acylating agents such as acyl chlorides or anhydrides to introduce acyl groups onto the nitrogen atom.
Ring Opening Reactions: The morpholine ring can undergo ring-opening reactions under acidic or basic conditions. For example, it can open to form a linear amine derivative.
Oxidation: Depending on the reaction conditions, (S)-3-phenylmorpholine can be oxidized to form various oxidation products. This may involve cleavage of the morpholine ring or oxidation of the phenyl group.
Reduction: The compound can also be reduced to form saturated derivatives.
Grignard Reactions: (S)-3-phenylmorpholine can react with Grignard reagents to form new carbon-carbon bonds.
Hydrolysis: The morpholine ring can undergo hydrolysis under acidic or basic conditions to produce corresponding amines and alcohols.
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(S)-3-(3-Bromo-5-chlorophenyl)morpholine
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(S)-3-(4-Methoxyphenyl)morpholine hydrochloride
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(S)-3-(4-Fluorophenyl)morpholine hydrochloride
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(S)-3-(4-Bromo-2,6-dichlorophenyl)morpholine
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