Home Chemistry Heterocyclic Building Blocks Indazoles 7-Chloro-1H-Indazole
Substitution Reactions: The chlorine atom can undergo substitution reactions, such as nucleophilic substitution or electrophilic substitution, with various nucleophiles or electrophiles to form substituted indazole derivatives.
Reduction: The chlorine atom can be reduced to a chloride ion or replaced with a hydrogen atom under appropriate conditions.
Functional Group Interconversion: The chlorine atom can be replaced or transformed into other functional groups through various chemical reactions, such as substitution reactions or elimination-addition reactions.
Metalation: The chlorine atom can undergo metalation reactions, where it is replaced by a metal atom, such as lithium, magnesium, or tin.
Cross-Coupling Reactions: The chlorine atom can participate in cross-coupling reactions, such as Suzuki coupling or Heck coupling, to form biaryl or aryl-heteroaryl compounds.
Halogenation: The chlorine atom can participate in halogenation reactions, where it can be replaced by other halogen atoms, such as bromine or iodine.
Oxidation: The chlorine atom can undergo oxidation reactions to form chlorinated compounds with higher oxidation states.
Rearrangement Reactions: The chlorine atom can participate in rearrangement reactions, leading to the formation of different regioisomers or tautomers of indazole derivatives.
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