Home Chemistry Organic building blocks Aldehydes 2-chloro-4-fluorobenzaldehyde
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Cl,—CHO,—F).
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
Wittig Reaction: Benzaldehyde can react with a phosphonium ylide in the presence of a base to form olefins (【alkenes|https://www.ambeed.com/alkenyls.html】) through the Wittig reaction.
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
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(4-Chloro-2-fluoro-5-formylphenyl)boronic acid
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