The Fibroblast Growth Factor (FGF) family consists of 22 members that function by binding to specific receptors, FGFRs. FGFs play a critical role in cell proliferation, differentiation, migration, and wound healing. They are expressed in a variety of cells and tissues, especially important in embryonic development and adult tissue repair. The interaction between FGFs and their receptors activates multiple signaling pathways, including the MAPK and PI3K/Akt pathways, thus affecting cell fate. The specific expression and mutations of genes are associated with the development of various diseases, such as cancer, developmental abnormalities, and metabolic diseases.