Chemistry Organic Building Blocks Aryls Diphenyl Phosphonate

Diphenyl Phosphonate

Phosphorylation Reactions: Diphenyl phosphonate can be used to introduce a phosphoryl group into organic molecules. For example, it can react with alcohols to form phosphate esters. The reaction involves the displacement of the hydrogen atom on the phosphorus atom with the alcohol group. Acylation Reactions: Diphenyl phosphonate can undergo acylation reactions with various nucleophiles. For instance, it can react with amines to form amides or with carboxylic acids to form mixed anhydrides. These reactions typically involve the displacement of one of the phenyl groups with the nucleophile. Reduction Reactions: The P(O)H group in diphenyl phosphonate can be reduced to form a phosphine oxide. This can be achieved by using reducing agents such as lithium aluminum hydride (LiAlH4). Cross-Coupling Reactions: Diphenyl phosphonate can be used as a coupling partner in cross-coupling reactions, such as the Heck reaction or Suzuki reaction, to form C-P bonds. In these reactions, the phenyl group can be replaced with another organic group. Phosphonylation of Nucleophiles: Diphenyl phosphonate can react with various nucleophiles, including amines and alcohols, to form phosphonate derivatives. This reaction involves the displacement of one of the phenyl groups with the nucleophile. Oxidation Reactions: The phenyl groups in diphenyl phosphonate can be oxidized to phenylphosphonic acid derivatives using strong oxidizing agents. This can lead to the formation of new C-P bonds. Halogenation Reactions: Diphenyl phosphonate can undergo halogenation reactions, such as bromination or chlorination, where the phenyl groups are substituted with halogen atoms.

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((2S,6S)-6-Phenoxytetrahydro-2H-Pyran-2-Yl)Methanol (2S,4S)-2-Phenoxytetrahydro-2H-Pyran-4-Yl Acetate (6-Phenoxytetrahydro-2H-Pyran-2-Yl)Methanol (8S,9S,14R)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-3H-Cyclopenta[A]Phenanthren-3-One (8S,9S,14R)-7,8,9,11,12,13,14,15,16,17-Decahydro-6H-Cyclopenta[A]Phenanthrene (9H-Fluoren-9-Yl)Methyl (2-(Tritylthio)Ethyl)Carbamate (9H-Fluoren-9-Yl)Methyl Cyclohexylcarbamate (Benzylsulfonyl)Benzene (Cyclopentyloxy)Benzene (E)-1-(2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One (E)-3-Styrylphenol 1,1-Dimethylcyclopropane 1,2-Bis(Diphenylphosphaneyl)Ethane 1,3,4,5-Tetrahydro-2H-Benzo[B]Azepin-2-One 1,3-Diphenylurea 1-(2-Hydroxyphenyl)-2-Phenylethan-1-One 1-(2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One 1-([1,1'-Biphenyl]-4-Yl)Ethan-1-One 1-(Naphthalen-2-Yl)Ethan-1-One 1-Benzyl-4-Chlorobenzene 1-Benzyl-4-Fluorobenzene 1-Bromonaphthalene 1-Chloronaphthalene 1-Fluoronaphthalene 1-Methoxynaphthalene 1-Methyl-4-(Phenylethynyl)Benzene 1-Methylnaphthalene 1-Naphthaldehyde 1-Naphthoic Acid 1-Nitronaphthalene 10H-Phenothiazine 2,2',3,3',5,5',6,6'-Octafluoro-1,1'-Biphenyl 2,5-Diphenylthiophene 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol 2-(Trifluoromethyl)-1,1'-Biphenyl 2-Benzylaniline 2-Bromo-1,1'-Biphenyl 2-Bromonaphthalene 2-Chloro-1,1'-Biphenyl 2-Chloronaphthalene 2-Ethoxynaphthalene 2-Fluorocyclopropane-1-Carboxylic Acid 2-Hydroxycyclohexa-2,5-Diene-1,4-Dione 2-Iodonaphthalene 2-Methoxy-1,1'-Biphenyl 2-Methoxynaphthalene 2-Methoxytetrahydro-2H-Pyran 2-Methyl-1,1'-Biphenyl 2-Methylnaphthalene 2-Naphthaldehyde 2-Naphthoic Acid 2-Naphthonitrile 2-Nitronaphthalene 2-Phenoxytetrahydro-2H-Pyran-4-Yl Acetate 2-Phenylnaphthalene 3,3'-Diphenyl-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthalene 3,3-Diphenyl-3H-Benzo[C][1,2]Oxathiole 1,1-Dioxide 3-Bromo-1,1'-Biphenyl 3-Chloro-1,1'-Biphenyl 3-Fluoro-1,1'-Biphenyl 3-Methyl-1,1'-Biphenyl 3-Methyl-1,1':4',1''-Terphenyl 3-Phenethylphenol 3-Phenyl-1,2,4,5-Tetrazine 3-Styrylphenol 4-(Bromomethyl)-1,1'-Biphenyl 4-(Phenyldiazenyl)Benzoic Acid 4-(Phenylsulfonyl)Morpholine 4-(Tert-Butyl)-1,1'-Biphenyl 4-Cyclohexylphenol 4-Iodo-1,1'-Biphenyl 4-Methoxy-1,1'-Biphenyl 9H-Xanthene [1,1'-Biphenyl]-2-Amine [1,1'-Biphenyl]-2-Carbonitrile [1,1'-Biphenyl]-2-Carboxylic Acid [1,1'-Biphenyl]-2-Ol [1,1'-Biphenyl]-3-Amine [1,1'-Biphenyl]-3-Carbaldehyde [1,1'-Biphenyl]-3-Carboxylic Acid [1,1'-Biphenyl]-3-Ol [1,1'-Biphenyl]-4-Carbaldehyde [1,1'-Biphenyl]-4-Carbonitrile [1,1'-Biphenyl]-4-Ol [1,1'-Biphenyl]-4-Ylboronic Acid Benzyltriphenylphosphonium Cyclopentylbenzene Cyclopropanecarboxylic Acid Cyclopropyl(Phenyl)Methanamine Cyclopropyl(Phenyl)Methanone Diphenyl Phosphonate Diphenylphosphane Diphenylphosphine Oxide Ethane-1,1-Diyldibenzene Ethene-1,1,2-Triyltribenzene Ethyl Cyclopropanecarboxylate Methyl 1-Naphthoate Methyl 2-Naphthoate Methyl [1,1'-Biphenyl]-4-Carboxylate Methyl Cyclopropanecarboxylate N,1-Diphenylmethanimine N,N-Dimethylnaphthalen-1-Amine N-((5R,6R)-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptan-6-Yl)-2-Phenylacetamide N-Benzylbenzamide N-Benzylbenzenesulfonamide N-Cyclopropylbenzamide N-Cyclopropylbenzenesulfonamide N-Phenethylbenzamide N-Phenyl-2-Naphthamide Naphthalen-1-Ol Naphthalen-1-Ylboronic Acid Naphthalen-1-Ylmethanol Naphthalen-2-Amine Naphthalen-2-Ol Naphthalen-2-Ylboronic Acid Naphthalene-1,4-Diol Naphthalene-2-Sulfonic Acid Propane-2,2-Diyldibenzene Tert-Butyl Cyclopropylcarbamate Tetrahydro-2H-Pyran-2-Ol Tetrahydro-2H-Pyran-2-Yl Acetate Tetraphenylmethane Triphenylene Vinylcyclopropane

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