Chemistry Organic Building Blocks Ethers 1,3-Diphenoxybenzene

1,3-Diphenoxybenzene

Electrophilic Aromatic Substitution (EAS): 1,3-Diphenoxybenzene can undergo electrophilic aromatic substitution reactions, where an electrophile substitutes one of the hydrogen atoms on the benzene ring. For example, it can react with strong electrophiles like nitration (HNO324) or sulfonation (H24). Friedel-Crafts Alkylation and Acylation: The compound can undergo Friedel-Crafts reactions to introduce alkyl or acyl groups onto the benzene ring. This requires the use of a Lewis acid catalyst such as AlCl3. Reduction: 1,3-Diphenoxybenzene can be reduced to form 1,3-diphenylcyclohexene by using reducing agents like hydrogen gas in the presence of a catalyst (e.g., Pd/C) or with a strong reducing agent like lithium aluminum hydride (LiAlH4). Oxidation: The compound can be oxidized to form quinone derivatives, which contain oxygen in the benzene ring. Common oxidizing agents like potassium permanganate (KMnO4) can be used for this purpose. Ether Cleavage: The phenoxy groups can be cleaved from the central benzene ring using strong acid or base conditions, resulting in the formation of phenol and an appropriate salt or phenoxide ion. Grignard Reaction: 1,3-Diphenoxybenzene can react with a Grignard reagent (e.g., phenylmagnesium bromide) to introduce a phenyl group onto the central benzene ring. Halogenation: It can undergo halogenation reactions, such as bromination or chlorination, to introduce halogen atoms onto the benzene ring.

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(1S,4Ar,7Ar)-1-(((S)-Tetrahydro-2H-Pyran-2-Yl)Oxy)-1,4A,5,7A-Tetrahydrocyclopenta[C]Pyran (2,2,2-Trifluoroethoxy)Benzene (2-(Benzyloxy)Phenyl)Boronic Acid (2-(Phenoxymethyl)Phenyl)Boronic Acid (2-Chloro-3-Methoxyphenyl)Boronic Acid (2-Chloroethoxy)Benzene (2-Methoxyethoxy)Benzene (3-(Benzyloxy)Phenyl)Boronic Acid (3-(Phenoxymethyl)Phenyl)Boronic Acid (3-Chloro-2-Methoxyphenyl)Boronic Acid (3-Phenoxyphenyl)Methanol (4-(Benzyloxy)Phenyl)Boronic Acid (4-(Phenoxymethyl)Phenyl)Boronic Acid (4-Methoxyphenyl)(Phenyl)Methanone (9H-Fluoren-9-Yl)Methyl (2-(Benzyloxy)Ethyl)Carbamate (9H-Fluoren-9-Yl)Methyl (4-Methoxybenzyl)Carbamate (Allyloxy)Benzene (Ethoxymethyl)Benzene (Hexyloxy)Benzene (Methoxymethyl)Benzene (Prop-2-Yn-1-Yloxy)Benzene (R)-2-Phenoxytetrahydro-2H-Pyran (S)-7-(((S)-Tetrahydro-2H-Pyran-2-Yl)Oxy)-7,8,9,10-Tetrahydrotetracene-5,12-Dione 1,2-Bis(Benzyloxy)Benzene 1,2-Dichloro-3-Methoxybenzene 1,2-Dichloro-4-Methoxybenzene 1,2-Difluoro-3-Methoxybenzene 1,2-Difluoro-4-Methoxybenzene 1,2-Dimethoxybenzene 1,2-Diphenoxyethane 1,3-Bis(Benzyloxy)Benzene 1,3-Dibromo-2-Methoxybenzene 1,3-Dichloro-2-Methoxybenzene 1,3-Diiodo-2-Phenoxybenzene 1,3-Dimethoxybenzene 1,3-Diphenoxybenzene 1,4-Dichloro-2-Methoxybenzene 1,4-Dimethoxybenzene 1-(2-Methoxyphenyl)Ethan-1-One 1-(3-(Benzyloxy)Phenyl)Ethan-1-One 1-(3-Methoxyphenyl)Ethan-1-One 1-(3-Methoxyphenyl)Piperazine 1-(4-(Benzyloxy)Phenyl)Ethan-1-One 1-(4-Methoxybenzyl)-1H-Pyrazole 1-(Benzyloxy)-2-Bromobenzene 1-(Benzyloxy)-2-Chlorobenzene 1-(Benzyloxy)-2-Fluorobenzene 1-(Benzyloxy)-2-Methoxybenzene 1-(Benzyloxy)-2-Methylbenzene 1-(Benzyloxy)-2-Nitrobenzene 1-(Benzyloxy)-3-Bromobenzene 1-(Benzyloxy)-3-Chlorobenzene 1-(Benzyloxy)-3-Fluorobenzene 1-(Benzyloxy)-3-Methylbenzene 1-(Benzyloxy)-3-Nitrobenzene 1-(Benzyloxy)-4-Bromobenzene 1-(Benzyloxy)-4-Iodobenzene 1-(Bromomethyl)-2-Methoxybenzene 1-(Bromomethyl)-3-Methoxybenzene 1-(Difluoromethoxy)-2-Fluorobenzene 1-Benzyl-4-Methoxybenzene 1-Bromo-2,3-Dimethoxybenzene 1-Bromo-2-Chloro-3-Methoxybenzene 1-Bromo-2-Ethoxybenzene 1-Bromo-2-Fluoro-3-Methoxybenzene 1-Bromo-2-Phenoxybenzene 1-Bromo-3-Methoxybenzene 1-Bromo-3-Phenoxybenzene 1-Bromo-4-Phenoxybenzene 1-Chloro-2,4-Dimethoxybenzene 1-Chloro-2-Ethoxybenzene 1-Chloro-2-Phenoxybenzene 1-Chloro-2-Propoxybenzene 1-Chloro-3-Fluoro-2-Methoxybenzene 1-Chloro-3-Methoxybenzene 1-Chloro-3-Phenoxybenzene 1-Chloro-4-Methoxybenzene 1-Chloro-4-Phenoxybenzene 1-Cyclopropyl-3-(4-(Quinolin-4-Yloxy)Phenyl)Urea 1-Ethoxy-2,3-Difluorobenzene 1-Ethoxy-2-Fluorobenzene 1-Ethoxy-3-Nitrobenzene 1-Fluoro-2-(Trifluoromethoxy)Benzene 1-Fluoro-2-Isopropoxybenzene 1-Fluoro-2-Phenoxybenzene 1-Fluoro-3-Methoxybenzene 1-Fluoro-3-Phenoxybenzene 1-Fluoro-4-(Trifluoromethoxy)Benzene 1-Fluoro-4-Methoxybenzene 1-Fluoro-4-Phenoxybenzene 1-Iodo-2-Methoxybenzene 1-Iodo-3-Methoxybenzene 1-Iodo-4-Methoxybenzene 1-Iodo-4-Phenoxybenzene 1-Methoxy-2-(Trifluoromethyl)Benzene 1-Methoxy-3-(Trifluoromethoxy)Benzene 1-Methoxy-3-(Trifluoromethyl)Benzene 1-Methoxy-3-Nitrobenzene 1-Methoxy-4-(Phenoxymethyl)Benzene 1-Methoxy-4-(Trifluoromethyl)Benzene 1-Methoxy-4-Nitrobenzene 1-Methoxynaphthalene 1-Methyl-3-Phenoxybenzene 1-Nitro-2-Phenoxybenzene 1-Nitro-4-Phenoxybenzene 1-Phenoxy-3-(Trifluoromethyl)Benzene 1-Phenoxy-4-(Trifluoromethyl)Benzene 1-Phenyl-3-(4-(Pyridin-4-Yloxy)Phenyl)Urea 2,3,5,6,8,9,11,12-Octahydrobenzo[B][1,4,7,10,13]Pentaoxacyclopentadecine 2,3-Dimethoxypyridine 2,4,6-Triphenoxy-1,3,5-Triazine 2,4-Dibromo-1-Methoxybenzene 2,4-Dichloro-1-Methoxybenzene 2,4-Difluoro-1-Methoxybenzene 2,4-Dimethoxy-1-Nitrobenzene 2,4-Dimethoxypyrimidine 2,6-Dimethoxypyridine 2-(2-Methoxyphenyl)Acetic Acid 2-(3-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(3-Methoxyphenyl)Acetic Acid 2-(4-(Benzyloxy)Phenyl)Acetonitrile 2-(4-Methoxyphenyl)Acetic Acid 2-(Benzyloxy)Benzaldehyde 2-(Benzyloxy)Naphthalene 2-(Benzyloxy)Phenol 2-(Methoxymethyl)Morpholine 2-(Methoxymethyl)Pyrrolidine 2-(Phenoxymethyl)Oxirane 2-(Phenoxymethyl)Pyridine 2-(Phenoxymethyl)Tetrahydro-2H-Pyran 2-Bromo-1,3-Dimethoxybenzene 2-Bromo-1,4-Dimethoxybenzene 2-Bromo-1-Fluoro-4-Methoxybenzene 2-Bromo-1-Methoxy-3-Methylbenzene 2-Bromo-1-Methoxy-4-Methylbenzene 2-Bromo-3-Methoxypyrazine 2-Bromo-4-Methoxy-1-Nitrobenzene 2-Bromo-4-Methoxyaniline 2-Bromo-4-Methoxybenzaldehyde 2-Bromo-4-Methoxybenzoic Acid 2-Bromo-5-Methoxybenzaldehyde 2-Bromo-6-Methoxyaniline 2-Bromo-6-Methoxyphenol 2-Chloro-1,3-Dimethoxybenzene 2-Chloro-1,4-Dimethoxybenzene 2-Chloro-3-Methoxybenzaldehyde 2-Chloro-3-Methoxybenzoic Acid 2-Chloro-4-Fluoro-1-Methoxybenzene 2-Chloro-4-Methoxypyrimidine 2-Chloro-5-Methoxyaniline 2-Chloro-6-Methoxyaniline 2-Chloro-6-Methoxyphenol 2-Ethoxynaphthalene 2-Ethoxypyridine 2-Ethoxypyrimidine 2-Fluoro-1,3-Dimethoxybenzene 2-Fluoro-1-Methoxy-4-Nitrobenzene 2-Fluoro-4-Methoxyaniline 2-Fluoro-5-Methoxybenzoic Acid 2-Fluoro-5-Methoxypyridine 2-Fluoro-6-Methoxypyridine 2-Isopropoxypyridine 2-Methoxy-1,1'-Biphenyl 2-Methoxy-1,3,5-Triazine 2-Methoxy-4-Methylpyridine 2-Methoxy-5-Methylpyridine 2-Methoxy-6-Methylpyridine 2-Methoxy-6-Nitrophenol 2-Methoxybenzamide 2-Methoxybenzenesulfonyl Chloride 2-Methoxynaphthalene 2-Methoxyphenol 2-Methoxypyrazine 2-Methoxypyridine 2-Methoxypyrimidin-4-Amine 2-Methoxypyrimidine 2-Methoxythiophene 2-Methyl-N-Phenylaniline 2-Phenoxyacetonitrile 2-Phenoxyaniline 2-Phenoxybenzonitrile 2-Phenoxyethan-1-Ol 2-Phenoxypropanoic Acid 2-Phenoxypyrimidine 2-Phenoxytetrahydro-2H-Pyran 2-Phenoxythiazole 2-Propoxypyridine 3,5-Dimethoxypyridine 3-(3-Methoxyphenyl)Propanoic Acid 3-(Benzyloxy)Aniline 3-(Benzyloxy)Benzaldehyde 3-(Benzyloxy)Benzoic Acid 3-(Benzyloxy)Phenol 3-(Methoxymethyl)Morpholine 3-Chloro-2-Methoxybenzoic Acid 3-Chloro-4-Methoxyaniline 3-Chloro-4-Methoxybenzaldehyde 3-Chloro-4-Methoxybenzoic Acid 3-Ethoxypyridine 3-Fluoro-2-Methoxypyridine 3-Fluoro-4-Methoxybenzoic Acid 3-Methoxypiperidine 3-Methoxypyridazine 3-Methoxypyridine 3-Methoxythiophene 3-Phenoxyaniline 3-Phenoxybenzaldehyde 3-Phenoxybenzoic Acid 3-Phenoxybenzonitrile 3-Phenoxypropanoic Acid 3-Phenoxypyrrolidine 4-(3-Phenoxypropyl)Morpholine 4-(Benzyloxy)Aniline 4-(Benzyloxy)Benzaldehyde 4-(Benzyloxy)Benzoic Acid 4-(Benzyloxy)Phenol 4-(Difluoromethoxy)Aniline 4-(Dimethoxymethyl)Pyrimidine 4-(Phenylethynyl)Phenol 4-Chloro-2-Methoxypyrimidine 4-Chloro-5-Methoxypyrimidine 4-Chloro-6-Methoxypyrimidine 4-Ethoxypyridine 4-Ethoxypyrimidine 4-Methoxy-1,1'-Biphenyl 4-Methoxy-1H-Indazole 4-Methoxy-1H-Indole 4-Methoxy-2-Methylpyrimidine 4-Methoxy-N-Phenylaniline 4-Methoxy-N-Phenylbenzenesulfonamide 4-Methoxybenzenesulfonamide 4-Methoxypyridazine 4-Methoxypyridine 4-Methoxypyrimidin-2-Amine 4-Methoxypyrimidine 4-Phenoxyaniline 4-Phenoxybenzaldehyde 4-Phenoxybenzoic Acid 4-Phenoxypyridine 4-Phenoxypyrimidine 4-Phenoxyquinoline 4-Phenoxytetrahydro-2H-Pyran 5-(Benzyloxy)Pyrimidine 5-Fluoro-2-Methoxypyridine 5-Methoxy-1H-Benzo[D]Imidazole 5-Methoxy-1H-Indazole 5-Methoxy-1H-Indole 5-Methoxy-2-Methyl-1H-Indole 5-Methoxy-2-Nitroaniline 5-Methoxyindoline 5-Methoxyisobenzofuran-1(3H)-One 5-Methoxyisoquinoline 6-Methoxy-1,2,3,4-Tetrahydroisoquinoline 6-Methoxy-1H-Indazole 6-Methoxy-1H-Indole 6-Methoxy-1H-Pyrrolo[2,3-B]Pyridine 6-Methoxy-3,4-Dihydroisoquinolin-1(2H)-One 6-Methoxybenzo[D]Thiazole 6-Methoxybenzofuran 6-Methoxychromane 6-Methoxyisoindolin-1-One 6-Methoxyquinoxaline 7-(Benzyloxy)Quinoline 7-Methoxy-1,2,3,4-Tetrahydroisoquinoline 7-Methoxy-1H-Indazole 7-Methoxy-1H-Indole 7-Methoxy-3,4-Dihydroquinolin-2(1H)-One 7-Methoxyisoquinoline 8-Methoxyisoquinoline 8-Methoxyquinazoline Butoxybenzene Ethoxybenzene Ethyl 2-Phenoxyacetate Isobutoxybenzene Isopropoxybenzene Methoxycyclohexane Methyl 2-Methoxybenzoate Methyl 2-Phenoxyacetate Methyl 2-Phenoxybenzoate Methyl 3-(Benzyloxy)Benzoate Methyl 3-Methoxybenzoate Methyl 4-Phenoxybenzoate N,N-Dimethyl-2-Phenoxyethan-1-Amine N-(2-Phenoxyphenyl)Methanesulfonamide N-(4-Phenoxyphenyl)Acetamide N-Phenyl-N-(4-(Quinolin-4-Yloxy)Phenyl)Cyclopropane-1,1-Dicarboxamide Phenethoxybenzene Propoxybenzene Tert-Butoxybenzene Tert-Butyl 3-Methoxypyrrolidine-1-Carboxylate Tert-Butyl 4-Phenoxypiperidine-1-Carboxylate Tert-Butyl 5-Methoxy-1H-Indole-1-Carboxylate

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(2-Ethylhexyl)Oxy (S)-2-Methoxyethanamine (Trimethylsilyl)Ethoxy 2,2,2-Trifluoroethoxy 2,2-Difluoroethoxy 2,2-Dimethoxyethyl 2-Bromo-1,1,2,2-Tetrafluoroethoxy 2-Bromoethoxy 2-Methoxyethoxy 2-Methoxyethoxymethyl 2-Methoxyethyl 2-Methyl-2-Oxypropanoic Acid 2-Oxoacetic Acid 2-Oxy-Propanoic Acid 3-(Oxy)Propanoic Acid 3-Methoxypropoxy 4-Bromobutoxy Allyloxy Benzo-Crown-Ether Butoxy Butoxy-Phenyl-Boronic Acid Butoxy-Phenyl-Boronic Acid/Ester Butoxy-Phenyl-Boronic-Acid Chloroanisole Cyanomethoxy Decyloxy Diethoxy Diethoxy Diethoxyethyl Diethoxyethyl Diethoxymethyl Diethoxymethyl Diethylaminoethoxy Dimethoxyethyl Dimethoxymethyl Dimethoxypropane Dimethoxypropane Dimethylamino Ethoxy Dimethylaminopropoxy Dioxane Dioxepine Dioxepine Dioxopropan Dioxopropan Disulfide Dodecyloxy Ethoxyethanol Ethyl 2-Oxyacetate Fluoromethoxy-Nitro-Benzene Heptyloxy Hexyloxy Isobutoxy Isopentyloxy Isopropoxy Isopropoxyphenylboronic Methoxy-Acetic Acid Methoxy-Benzoimidazole Methoxy-Carbazole Methoxy-Chromen-One Methoxy-Indanone Methoxy-Indazole-Carboxylate Methoxy-Inden-Amine Methoxy-Indole-Carboxylate Methoxy-Methyl-Indole Methoxy-Methylbenzene Methoxy-Naphthyridine Methoxy-Pyran Methoxy-Pyrazolo-Pyridine Methoxy-Trifluoromethyl-Benzene Methoxyacetate Methoxychroman Methoxyethoxyethoxyethoxy Methoxyphenylboronic-Acid Methyl 2-Oxy-Acetate Nitroanisole Octyloxy Oxy Ethanamine Oxy-Acetohydrazide Oxyacetic Acid Oxypropane-1,2-Dio Prop-2-Yn-1-Oxy Propoxy Tert-Butoxy Tert-Butoxybromobenzene Tert-Butoxymethyl Tetrahydroquinoline-Methoxy

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