Home Chemistry Heterocyclic Building Blocks Imidazoles 4-Phenyl-1H-Imidazole
Alkylation: You can alkylate the nitrogen atom using alkyl halides or alkylating agents to form N-alkylated imidazoles.
Halogenation: The phenyl group can undergo halogenation reactions (e.g., bromination or chlorination) to introduce halogen atoms onto the phenyl ring.
Reduction: The imidazole ring can be reduced using reducing agents like sodium borohydride (NaBH4) to form dihydroimidazoles.
Substitution reactions: Various substitution reactions can occur on the imidazole ring, depending on the reagents and conditions. For example, you can substitute hydrogen with other functional groups using appropriate reagents.
Ring-closure reactions: 4-phenyl-1H-imidazole can participate in ring-closure reactions to form cyclic compounds if suitable reactants are available.
Condensation reactions: It can undergo condensation reactions with carbonyl compounds to form various heterocyclic compounds.
Metalation reactions: The imidazole ring can coordinate with metal ions, forming metal complexes.
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(S)-1-(4-Phenyl-1H-imidazol-2-yl)ethanamine
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Ethyl 4-phenyl-1H-imidazole-5-carboxylate
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5-Bromo-4-phenyl-1H-imidazole-2-carbaldehyde
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4-(4-(Trifluoromethyl)phenyl)-1H-imidazole
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