Home Chemistry Organic Building Blocks Fluorinated Building Blocks Ethyl 3-Fluorobenzoate
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—COOC2H5).
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Reduction: Ethyl benzoate can be reduced to ethyl benzyl alcohol using reducing agents like lithium aluminum hydride (LiAlH4). This involves the reduction of the carbonyl group (C=O) in the ester to a hydroxyl group (–OH).
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(2-(Ethoxycarbonyl)-4-fluorophenyl)boronic acid
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(3-(Ethoxycarbonyl)-5-fluorophenyl)boronic acid
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2-Fluoro-4-ethoxycarbonylphenylboronic acid
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Ethyl 3-fluoro-4-(trifluoromethyl)benzoate
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