Home Chemistry Organic Building Blocks Trifluoromethyls (2,2,2-Trifluoroethoxy)Benzene
These compounds have the same murcko framework: benzene,and at least 1 kind of functional groups( —OCH2CF3).
Electrophilic Aromatic Substitution (EAS): In EAS reactions, the aromatic ring in benzene can undergo substitution reactions when exposed to electrophiles. The substituent groups on the benzene ring can influence the reactivity. The presence of electron-withdrawing groups like trifluoro groups can activate the ring toward electrophilic substitution. Depending on the reaction conditions and the electrophile used, you could see reactions like nitration, sulfonation, or Friedel-Crafts acylation/alkylation.
Nucleophilic Aromatic Substitution (SNAr): The ethoxy group in (2,2,2-trifluoroethoxy)benzene could be a target for nucleophilic substitution reactions. Nucleophiles could potentially displace the ethoxy group in a reaction known as SNAr. The reactivity will depend on the choice of nucleophile and reaction conditions.
Other Reactions: Depending on the reaction conditions and the specific reagents used, various other reactions, such as halogenation, oxidation, or rearrangements, may be possible. The exact reaction that occurs will depend on the experimental setup and the desired outcome.
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(2-(2,2,2-Trifluoroethoxy)phenyl)boronic acid
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(3-(2,2,2-Trifluoroethoxy)phenyl)boronic acid
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(4-(2,2,2-Trifluoroethoxy)phenyl)hydrazine hydrochloride
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2-(2-(2,2,2-Trifluoroethoxy)phenoxy)ethyl methanesulfonate
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3-Methyl-4-(2,2,2-trifluoroethoxy)aniline
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(4-Fluoro-3-(2,2,2-trifluoroethoxy)phenyl)boronic acid
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4-Bromo-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene
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(3-Fluoro-4-(2,2,2-trifluoroethoxy)phenyl)boronic acid
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5-Bromo-1,3-difluoro-2-(2,2,2-trifluoroethoxy)benzene
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1-(2-Bromoethoxy)-2-(2,2,2-trifluoroethoxy)benzene
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4-Fluoro-1-nitro-2-(2,2,2-trifluoroethoxy)benzene
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4-(2,2,2-Trifluoroethoxy)benzeneboronic acid
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