Home Chemistry Organometallic Reagents Organoborons 2-(4-Cyclopropylphenyl)-1,3,2-Dioxaborolane
Buchwald-Hartwig Amination: This reaction involves coupling the dioxaborolane with primary or secondary amines in the presence of a palladium catalyst and a base to form N-arylated or N-alkylated products.
Hydroboration: 2-(4-cyclopropylphenyl)-1,3,2-dioxaborolane can undergo hydroboration reactions with boron reagents (e.g., BH3·THF) to introduce boron-containing groups, which can be further elaborated through various transformations.
Oxidation: The boron atom in 2-(4-cyclopropylphenyl)-1,3,2-dioxaborolane can be oxidized to generate a boronic acid, which can then be used in various reactions, such as Suzuki-Miyaura cross-coupling or other boron-based transformations.
Halogenation: The phenyl ring in this compound can undergo halogenation reactions (e.g., bromination or chlorination) when treated with suitable halogenating agents, producing substituted derivatives.
Reductive Transformations: The compound can be subjected to various reductive transformations using reducing agents such as sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4) to reduce functional groups like ketones or aldehydes within the molecule.
Other Functional Group Transformations: The cyclopropyl group and the phenyl group in the molecule can participate in various reactions like ring-opening reactions, ring-closing reactions, or substitution reactions, depending on the reaction conditions and reagents used.
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(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropyl)methanol
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Methyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate
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Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate
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tert-Butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropyl)carbamate
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4-Cyclopropylphenylboronic Acid Pinacol Ester
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1-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carbonitrile
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1-(3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarbonitrile
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1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarbonitrile
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