Home Chemistry Organometallic Reagents Organoborons 2-(Furan-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
Stille Coupling: Similar to Suzuki-Miyaura coupling, it can also undergo Stille coupling reactions with organostannanes in the presence of a palladium catalyst. This reaction is useful for the formation of carbon-carbon bonds.
Buchwald-Hartwig Amination: The compound can be used in Buchwald-Hartwig amination reactions, which involve the coupling of aryl or vinyl halides with amines in the presence of a palladium catalyst and a base. This is a valuable reaction for the synthesis of various amines.
Boronic Acid Derivative: The boron atom in the compound can be converted to a boronic acid or boronic ester, which can then participate in other reactions like Suzuki-Miyaura coupling or as a precursor in the formation of other functional groups.
Hydrogenation: The furan ring in the compound can be hydrogenated using a suitable hydrogenation catalyst, such as palladium on carbon, to yield a saturated product.
Cross-Coupling Reactions: Depending on the substrate and reaction conditions, this compound can undergo various cross-coupling reactions with different electrophiles (e.g., halides) to form new carbon-carbon or carbon-heteroatom bonds.
Functional Group Transformations: The furan ring and boron atom in the compound can serve as functional groups for further synthetic manipulations, such as oxidation, reduction, or substitution reactions.
Protecting Group: The furan ring can be used as a protecting group for certain functional groups in organic synthesis and can be selectively removed when needed.
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2-(2-Furanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carboxylic acid
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4,4,5,5-Tetramethyl-2-(5-methylfuran-2-yl)-1,3,2-dioxaborolane
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylic acid
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carbaldehyde
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