Home Chemistry Heterocyclic building blocks Indazoles (1h-indazol-6-yl)boronic acid
Suzuki-Miyaura Coupling: (1H-indazol-6-yl)boronic acid can undergo Suzuki-Miyaura coupling reactions with aryl halides or pseudohalides in the presence of a palladium catalyst and a base to form biaryl compounds.
Borylation Reactions: (1H-indazol-6-yl)boronic acid can be used as a boron source in various borylation reactions, such as Chan-Lam coupling, Miyaura borylation, or hydroboration, to introduce boron functionalities into organic molecules.
Transition Metal-Catalyzed Cross-Coupling Reactions: It can participate in various transition metal-catalyzed cross-coupling reactions, such as Heck coupling, Sonogashira coupling, or Buchwald-Hartwig amination, to form C-C or C-N bonds.
Direct C-H Functionalization: (1H-indazol-6-yl)boronic acid can undergo direct C-H functionalization reactions to introduce functional groups onto the indazole ring.
Boronate Ester Formation: It can react with alcohols or diols in the presence of a Lewis acid to form boronate esters.
Halogenation Reactions: (1H-indazol-6-yl)boronic acid can undergo halogenation reactions to introduce halogen atoms onto the indazole ring.
Redox Reactions: It can participate in redox reactions, such as oxidation or reduction, to convert the boronic acid group into other functional groups.
Metalation Reactions: (1H-indazol-6-yl)boronic acid can undergo metalation reactions to form metal complexes, which can further participate in various organic transformations.
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(5-Methyl-1H-indazol-6-yl)boronic acid
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