The FPR (Formyl Peptide Receptor) family is a member of the G protein-coupled receptor family, mainly including FPR1, FPR2, and FPR3. These receptors consist of seven transmembrane domains and are primarily located on the surface of neutrophils, macrophages, and dendritic cells. The FPR family is involved in regulating inflammation and immune responses by recognizing peptides produced by bacteria or inflammatory mediators produced by the host. They activate downstream signaling pathways such as PI3K/Akt and MAPK, promoting cell migration, phagocytosis, and cytokine production. The expression of FPR is specific in different cells and tissues, and mutations or dysregulation in its gene expression are associated with the occurrence and development of various inflammatory diseases, infections, and tumors.