Home Chemistry Heterocyclic Building Blocks Indazoles 6-(Trifluoromethyl)-1H-Indazole
Substitution Reactions: The trifluoromethyl group can undergo nucleophilic substitution reactions with various nucleophiles, leading to the formation of substituted trifluoromethyl compounds.
Electrophilic Aromatic Substitution: The aromatic ring can undergo electrophilic aromatic substitution reactions with electrophiles, such as nitration, halogenation, sulfonation, or Friedel-Crafts reactions.
Reduction: The trifluoromethyl group or other functional groups present can be reduced using reducing agents to form the corresponding derivatives.
Oxidation: The indazole ring or other functional groups present can be oxidized using oxidizing agents to form the corresponding derivatives.
Halogenation: The indazole ring can undergo halogenation reactions, introducing halogen atoms at various positions.
Amidation: The indazole ring can react with amines or amides to form amide derivatives.
Alkylation: The nitrogen atom in the indazole ring can be alkylated by reaction with alkyl halides or sulfonates.
Cyclization Reactions: The indazole ring can undergo cyclization reactions under certain conditions, leading to the formation of fused heterocyclic compounds.
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3-Bromo-6-(trifluoromethyl)-1H-indazole
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5-Nitro-6-(trifluoromethyl)-1H-indazole
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