Home Chemistry Heterocyclic Building Blocks Piperidines 2-Methylpiperidine
N-Alkylation: The nitrogen atom in the piperidine ring can undergo alkylation reactions with alkyl halides or alkylating agents, leading to the formation of N-alkylpiperidines.
Ring Substitution Reactions: The methyl group can undergo substitution reactions on the piperidine ring, such as electrophilic aromatic substitution or nucleophilic substitution at the α-carbon of the ring.
Reduction: The carbonyl group present in the side chain of 2-methyl piperidine can be reduced to the corresponding alcohols using reducing agents like lithium aluminum hydride or sodium borohydride.
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tert-Butyl 4-hydroxy-2-methylpiperidine-1-carboxylate
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tert-Butyl (2-methylpiperidin-3-yl)carbamate
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cis-1-(tert-Butoxycarbonyl)-6-methylpiperidine-3-carboxylic acid
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tert-Butyl ((2R,4R)-2-methylpiperidin-4-yl)carbamate
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(2S,4R)-tert-Butyl 4-hydroxy-2-methylpiperidine-1-carboxylate
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(2R,4S)-rel-tert-Butyl 4-hydroxy-2-methylpiperidine-1-carboxylate
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(2R,4R)-tert-Butyl 4-hydroxy-2-methylpiperidine-1-carboxylate
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tert-Butyl (2,6-dimethylpiperidin-4-yl)carbamate
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tert-Butyl (2R,4R)-4-amino-2-methylpiperidine-1-carboxylate
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