Home Chemistry Heterocyclic Building Blocks Pyrrolidines Tert-Butyl Pyrrolidin-3-Ylcarbamate
Nucleophilic Substitution: The carbamate group can undergo nucleophilic substitution reactions at the carbon attached to the nitrogen atom. This can result in displacement of the tert-butyl group by a nucleophile.
Hofmann Elimination: Under strongly basic conditions, tert-butyl pyrrolidin-3-ylcarbamate can undergo Hofmann elimination to yield the corresponding alkene and tert-butylamine.
Reduction: The carbonyl group of the carbamate can be reduced to the corresponding alcohol under appropriate conditions.
Ring-opening Reactions: The pyrrolidine ring may undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
Protection Reactions: The tert-butyl group can serve as a protecting group for the amine functionality, allowing selective reactions at other functional groups.
Substitution Reactions: The tert-butyl group can undergo substitution reactions, such as nucleophilic substitution or electrophilic substitution.
Hydrolysis: Under acidic or basic conditions, the carbamate group can undergo hydrolysis to form the corresponding amine and tert-butanol.
Oxidation: The tert-butyl group can be oxidized to the corresponding alcohol or carbonyl compound under suitable conditions.
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tert-Butyl ((3R,4R)-4-hydroxypyrrolidin-3-yl)carbamate hydrochloride
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tert-Butyl (3R,4S)-4-methylpyrrolidin-3-ylcarbamate hydrochloride
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rel-tert-Butyl ((3R,4R)-4-methylpyrrolidin-3-yl)carbamate hydrochloride
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(R)-tert-Butyl pyrrolidin-3-ylcarbamate hydrochloride
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tert-Butyl (4-methylpyrrolidin-3-yl)carbamate hydrochloride
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tert-Butyl pyrrolidin-3-ylcarbamate hydrochloride
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tert-Butyl ((3S,4S)-4-methylpyrrolidin-3-yl)carbamate hydrochloride
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tert-Butyl (3S,4R)-4-methylpyrrolidin-3-ylcarbamate hydrochloride
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tert-Butyl ((3R,4R)-4-hydroxypyrrolidin-3-yl)carbamate
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