Home Chemistry Organic Building Blocks Trifluoromethyls 3-(Trifluoromethoxy)Aniline
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —OCF3,—NH2).
Grignard Reactions: Trifluoromethoxybenzene can react with Grignard reagents to form new carbon-carbon bonds. This is often used to introduce alkyl or aryl groups onto the benzene ring.
Coupling Reactions: Aniline can participate in coupling reactions, such as Ullmann coupling, Buchwald-Hartwig coupling, and others, to form C-N bonds with various partner molecules.
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4-Chloro-5-(trifluoromethoxy)benzene-1,2-diamine
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3-Fluoro-5-(trifluoromethoxy)aniline hydrochloride
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2,4-Difluoro-5-(trifluoromethoxy)aniline
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