Home Chemistry Heterocyclic Building Blocks Pyrrolidines Hexahydro-1H-Pyrrolizine
Hydrogenation: Hexahydro-1H-pyrrolizine can be hydrogenated to produce piperidine, which is a six-membered saturated nitrogen-containing ring compound. This reaction typically involves the use of a hydrogen gas source and a catalyst like platinum or palladium.
N-alkylation: The nitrogen atom in hexahydro-1H-pyrrolizine can be alkylated using alkyl halides or other alkylating agents. This can result in the formation of various N-substituted pyrrolizidine derivatives.
Ring-opening reactions: Hexahydro-1H-pyrrolizine can undergo ring-opening reactions under certain conditions, such as with strong acids or bases. This can lead to the formation of different products, depending on the reagents and reaction conditions.
Oxidation: Hexahydro-1H-pyrrolizine can be oxidized to form various compounds. The specific products of oxidation depend on the choice of oxidizing agent and reaction conditions.
Reaction with electrophiles: Hexahydro-1H-pyrrolizine can react with electrophilic reagents, leading to the addition of various functional groups to the ring structure. This can result in the formation of substituted pyrrolizidine derivatives.
Reduction: Hexahydro-1H-pyrrolizine can be reduced using reducing agents to form compounds with fewer hydrogen atoms.
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2-(Hexahydro-1H-pyrrolizin-7a-yl)acetonitrile
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Methyl 3-(hydroxymethyl)hexahydro-1H-pyrrolizine-7a-carboxylate
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Methyl hexahydro-1H-pyrrolizine-7a-carboxylate
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((2R,7aS)-2-Fluorohexahydro-1H-pyrrolizin-7a-yl)methanol
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((2R,7aS)-2-Fluorohexahydro-1H-pyrrolizin-7a-yl)methanol hydrochloride
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1-(Hexahydro-1H-pyrrolizin-7a-yl)ethanone
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N-((Hexahydro-1H-pyrrolizin-7a-yl)methyl)ethanamine
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Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid hydrochloride
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1-(Hexahydro-1H-pyrrolizin-7a-yl)-N-methylmethanamine
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Hexahydro-1H-pyrrolizine-7a-carbonitrile
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