Home Chemistry Organic Building Blocks Chlorides 1-Chloro-2-(Trifluoromethyl)Benzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—CF3).
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
Oxidation: Oxidation reactions could lead to the conversion of the trifluoromethyl group to a carbonyl group (e.g., trifluoromethyl ketone).
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5-Chloro-2-fluoro-4-(trifluoromethyl)aniline
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1-Bromo-3-chloro-2-(trifluoromethyl)benzene
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2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene
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4-(Bromomethyl)-1-chloro-2-(trifluoromethyl)benzene
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(4-Chloro-3-(trifluoromethyl)phenyl)hydrazine hydrochloride
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(S)-2-Amino-2-(4-chloro-3-(trifluoromethyl)phenyl)ethanol hydrochloride
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2-Chloro-4-nitro-1-(trifluoromethyl)benzene
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4-Chloro-3-(trifluoromethyl)phenylacetic acid
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2-Bromo-4-chloro-5-(trifluoromethyl)phenol
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2-Chloro-3,5-bis(trifluoromethyl)aniline
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(R)-2-Amino-2-(4-chloro-3-(trifluoromethyl)phenyl)ethanol hydrochloride
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2-Bromo-5-chloro-4-(trifluoromethyl)aniline
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1-(Bromomethyl)-2-chloro-3-(trifluoromethyl)benzene
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2-Bromo-1-(4-chloro-3-(trifluoromethyl)phenyl)ethanone
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