Home Chemistry Heterocyclic Building Blocks Pyridines Tert-Butyl Pyridin-2-Ylcarbamate
Hydrolysis: Tert-butyl pyridin-2-ylcarbamate can undergo hydrolysis in the presence of water or aqueous acids or bases, yielding the corresponding carboxylic acid and amine.
Nucleophilic Substitution: The carbamate group in tert-butyl pyridin-2-ylcarbamate is susceptible to nucleophilic substitution reactions. Nucleophiles can attack the carbonyl carbon, leading to substitution of the carbamate group with the nucleophile.
Oxidation: Depending on the conditions, tert-butyl pyridin-2-ylcarbamate can undergo oxidation reactions. For example, it may be oxidized to its corresponding N-oxide or other oxidized products.
Reduction: Conversely, it can also undergo reduction reactions, where the carbonyl group of the carbamate can be reduced to an alcohol or other reduced forms.
Metal Complexation: The pyridine moiety in tert-butyl pyridin-2-ylcarbamate can coordinate with metal ions, forming metal complexes. These complexes may have various applications in catalysis or material science.
Condensation Reactions: Tert-butyl pyridin-2-ylcarbamate may participate in condensation reactions with appropriate reagents, leading to the formation of various heterocyclic compounds or other products.
Acylation: The nitrogen atom in the pyridine ring can undergo acylation reactions, where an acyl group is transferred to the nitrogen atom, resulting in the formation of amides.
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tert-Butyl (6-chloro-3-iodopyridin-2-yl)carbamate
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tert-Butyl (4-chloropyridin-2-yl)carbamate
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tert-Butyl (4-fluoropyridin-2-yl)carbamate
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tert-Butyl (4-bromopyridin-2-yl)carbamate
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tert-Butyl (4-methylpyridin-2-yl)carbamate
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