Home Chemistry Organic Building Blocks Fluorinated Building Blocks (2,3-Difluorophenyl)Boronic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—B(OH)2).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Aromatic Substitution Reactions: Phenylboronic acid can undergo nucleophilic aromatic substitution reactions, especially under certain conditions. These reactions can lead to the formation of various functionalized aromatic compounds.
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(5-Chloro-2,3-difluorophenyl)boronic acid
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4-(t-Butyldimethylsilyloxy)-2,3-difluorophenylboronic acid
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(2,3-Difluoro-4-methylphenyl)boronic acid
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(4-Bromo-2,3,5,6-tetrafluorophenyl)boronic acid
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(6-Chloro-2,3-difluorophenyl)boronic acid
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(4-Ethoxy-2,3-difluorophenyl)boronic acid
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(5-Bromo-2,3-difluoro-4-methoxyphenyl)boronic acid
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(6-Ethoxy-2,3-difluorophenyl)boronic acid
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(5-Bromo-2,3-difluorophenyl)boronic acid
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4-Bromo-2,3-difluorobenzeneboronic acid
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(2,3-Difluoro-4-methoxyphenyl)boronic acid
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(2,3-Difluoro-4-hydroxyphenyl)boronic acid
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(2,3-Difluoro-4-propoxyphenyl)boronic acid
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(2,3,4,5-Tetrafluorophenyl)boronic acid
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4-Chloro-2,3-difluorophenylboronic acid
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