Home Chemistry Heterocyclic Building Blocks Oxadiazoles 1,2,5-Oxadiazole
Nitration: 1,2,5-Oxadiazole can be nitrated by treating it with a mixture of nitric acid and sulfuric acid to introduce nitro groups (-NO2) at various positions on the ring.
Reduction: Reduction of the oxadiazole ring can be achieved using reducing agents like hydrogen gas over a catalyst or metal hydrides. This can lead to the formation of corresponding dihydro-1,2,5-oxadiazoles.
Halogenation: 1,2,5-Oxadiazole can be halogenated by using halogenating agents such as bromine or chlorine. This results in the introduction of halogen atoms onto the ring.
Acylation and Alkylation: The oxadiazole ring can undergo acylation and alkylation reactions with appropriate acyl or alkyl halides in the presence of a base or other catalysts.
Cyclization Reactions: 1,2,5-Oxadiazole can participate in various intramolecular cyclization reactions to form fused ring systems or other heterocyclic compounds.
Oxidation: Oxidation reactions can convert 1,2,5-oxadiazole into its corresponding N-oxide or other oxidation products.
Substitution Reactions: Like many heterocyclic compounds, 1,2,5-oxadiazole can undergo substitution reactions, where one atom or group is replaced by another atom or group.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
4-Amino-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
click to sign in and save
4-Amino-N-hydroxy-1,2,5-oxadiazole-3-carbimidoyl chloride
click to sign in and save
Ethyl 4-amino-1,2,5-oxadiazole-3-carboxylate
click to sign in and save
Methyl 4-amino-1,2,5-oxadiazole-3-carboxylate
click to sign in and save
4-Amino-1,2,5-oxadiazole-3-carboxylic acid
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :